Pezner R D, Patterson M P, Hill L R, Vora N, Desai K R, Archambeau J O, Lipsett J A
Int J Radiat Oncol Biol Phys. 1985 Mar;11(3):575-8. doi: 10.1016/0360-3016(85)90190-7.
Breast Retraction Assessment (BRA) is an objective evaluation of the amount of cosmetic retraction of the treated breast in comparison to the untreated breast in patients who receive conservative treatment for breast cancer. A clear acrylic sheet supported vertically and marked as a grid at 1 cm intervals is employed to perform the measurements. Average BRA value (+/- standard deviation) in 29 control patients without breast cancer was 1.2 cm (+/- 0.7 cm). Average BRA value in 27 patients treated conservatively for clinical Stage I or II unilateral breast cancer was 3.7 cm (+/- 2.1 cm). BRA values in breast cancer patients ranged from 0.0 to 8.5 cm. Statistical analysis revealed that tumor size, employment of adjuvant chemotherapy and use of separate radiation lymph node fields were not factors in breast retraction. Patients who received a local radiation boost to the primary tumor bed site had statistically significantly less retraction than those who did not receive a boost. Patients who had an extensive primary tumor resection had statistically significantly more retraction than those who underwent a more limited resection. In comparison to qualitative forms of cosmetic analysis, BRA is an objective test that can quantitatively evaluate factors which may be related to cosmetic retraction in patients treated conservatively for breast cancer.
乳房回缩评估（BRA）是对接受乳腺癌保守治疗的患者中，治疗侧乳房与未治疗侧乳房相比的美容性回缩量进行的客观评估。使用一块垂直支撑且每隔1厘米标有网格的透明丙烯酸板进行测量。29名无乳腺癌的对照患者的平均BRA值（±标准差）为1.2厘米（±0.7厘米）。27名接受临床I期或II期单侧乳腺癌保守治疗的患者的平均BRA值为3.7厘米（±2.1厘米）。乳腺癌患者的BRA值范围为0.0至8.5厘米。统计分析显示，肿瘤大小、辅助化疗的使用以及单独的放射淋巴结野的使用并非乳房回缩的因素。对原发肿瘤床部位进行局部放疗加量的患者，其回缩在统计学上显著少于未接受加量放疗的患者。进行广泛原发肿瘤切除的患者，其回缩在统计学上显著多于进行更有限切除的患者。与定性的美容分析形式相比，BRA是一种客观测试，可定量评估可能与乳腺癌保守治疗患者的美容回缩相关的因素。
