Brown M D, Kohorn E I, Kapp D S, Schwartz P E, Merino M
Int J Radiat Oncol Biol Phys. 1985 Mar;11(3):583-90. doi: 10.1016/0360-3016(85)90192-0.
Twenty-one patients with fallopian tube carcinoma from Yale-New Haven Medical Center are reviewed. Most patients who died of disease did so in the first two years after diagnosis, even following complete resection, clearly indicating the need for adjuvant therapy. Negative second-look surgery did not provide assurance of permanent remission. There was a high recurrence rate with Stage I and completely resected Stage II and III disease (8 of 14 patients). Some recurrences occurred late, up to nine years after initial diagnosis. We recommend whole abdomino-pelvic radiation if no disease greater than 2 cm3 bulk exists after surgery. Chemotherapy may be an alternative to radiation as primary adjuvant treatment in early stage disease. Chemotherapy for unresectable disease or recurrent disease has shown palliation with occasional prolonged survival but no patient with recurrent disease survived longer than two years.
对来自耶鲁-纽黑文医疗中心的21例输卵管癌患者进行了回顾性研究。大多数死于该疾病的患者在诊断后的头两年内死亡，即使是在完全切除术后，这清楚地表明需要辅助治疗。二次探查手术结果为阴性并不能保证永久缓解。Ⅰ期以及完全切除的Ⅱ期和Ⅲ期疾病的复发率很高（14例患者中有8例）。一些复发出现较晚，在初次诊断后长达九年。如果术后不存在体积大于2 cm³的病灶，我们建议进行全腹盆腔放疗。在早期疾病中，化疗可作为主要辅助治疗替代放疗。对于无法切除的疾病或复发性疾病，化疗已显示出姑息作用，偶尔可延长生存期，但没有复发性疾病患者存活超过两年。
