莱氏无胆甾原体B-PG9中的嘧啶脱氧核糖核苷酸代谢
Pyrimidine deoxyribonucleotide metabolism in Acholeplasma laidlawii B-PG9.
作者信息
Williams M V, Pollack J D
出版信息
J Bacteriol. 1985 Mar;161(3):1029-33. doi: 10.1128/jb.161.3.1029-1033.1985.
Abstract
Extracts of Acholeplasma laidlawii B-PG9 were examined for the enzymes associated with the interconversion of the pyrimidine deoxyribonucleotides and the biosynthesis of thymidine nucleotides. A. laidlawii B-PG9 possessed deaminases for deoxycytidine and dCMP, pyrophosphatases for dUTP, phosphorylases for thymidine and uridine, and a membrane-associated pyrimidine deoxyribonucleoside monophosphate phosphatase activity. The role these enzyme activities have in the generation of deoxyribose-1-phosphate during growth may explain the ability of A. laidlawii B-PG9 to utilize either thymine or thymidine for biosynthesis.
摘要
对莱氏无胆甾原体B-PG9的提取物进行了检测，以寻找与嘧啶脱氧核糖核苷酸的相互转化及胸苷核苷酸生物合成相关的酶。莱氏无胆甾原体B-PG9具有脱氧胞苷和dCMP脱氨酶、dUTP焦磷酸酶、胸苷和尿苷磷酸化酶，以及一种与膜相关的嘧啶脱氧核糖核苷单磷酸磷酸酶活性。这些酶活性在生长过程中对脱氧核糖-1-磷酸生成所起的作用，可能解释了莱氏无胆甾原体B-PG9利用胸腺嘧啶或胸苷进行生物合成的能力。
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1
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J Gen Microbiol. 1962 Jun;28:243-50. doi: 10.1099/00221287-28-2-243.
2
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Ann N Y Acad Sci. 1960 Jan 15;79:499-507. doi: 10.1111/j.1749-6632.1960.tb42716.x.
3
NUCLEASES OF MYCOPLASMA.支原体的核酸酶
J Gen Microbiol. 1964 Aug;36:323-32. doi: 10.1099/00221287-36-2-323.
4
A thin-layer chromatographic method for separation of thymidine and deoxyuridine nucleotides.
Anal Biochem. 1980 Jul 1;105(2):311-8. doi: 10.1016/0003-2697(80)90463-7.
5
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6
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J Bacteriol. 1982 Oct;152(1):538-41. doi: 10.1128/jb.152.1.538-541.1982.
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