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减少自体乳房重建术后皮瓣坏死:一项系统评价。

Reduce Flap Necrosis After Autologous Breast Reconstruction: A Systematic Review.

作者信息

Gao Yiwen, Yin Lu, Xiang Tinghong, Ni Tianyi, Shi Jingping

机构信息

Department of Burn and Plastic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P. R. China.

出版信息

J Craniofac Surg. 2025 Sep 1;36(6):e598-e605. doi: 10.1097/SCS.0000000000011060. Epub 2024 Dec 27.

Abstract

BACKGROUND

Autologous breast reconstruction provides substantial benefits in terms of aesthetics and longevity. However, the risk of flap necrosis poses potential challenges to patients' appearance and psychological well-being, while also escalating health care costs. Consequently, examining the risk factors, assessment techniques, and therapeutic approaches for flap necrosis is critically important.

METHOD

The authors conducted a comprehensive search for relevant studies from January 2010 to August 2024 using PubMed, Web of Science, and the Cochrane Library. The search terms included "autologous breast reconstruction", "flap necrosis", "risk factor", "assessment", and "treatment". The authors initially screened titles and abstracts, followed by a detailed review by 3 investigators to determine the studies that met the inclusion criteria.

RESULT

A total of 68 studies were ultimately selected for analysis. Identified risk factors for flap necrosis include smoking, advanced age, obesity, diabetes, large breast volume, previous radiotherapy, and abdominal surgery. Various assessment methods (e.g., preoperative imaging, intraoperative blood flow monitoring, and postoperative evaluations) can enhance flap survival. The review also covered surgical treatment strategies and non-surgical interventions, including local wound care, hyperbaric oxygen therapy, and pharmacological treatments.

CONCLUSION

This review highlights the critical role of thorough planning and management in minimizing the risk of flap necrosis after autologous breast reconstruction. Effective preoperative assessments, perioperative monitoring, and specific postoperative interventions can significantly lower the incidence of flap necrosis.

摘要

背景

自体乳房重建在美学和持久性方面具有显著优势。然而,皮瓣坏死的风险对患者的外观和心理健康构成了潜在挑战,同时也增加了医疗成本。因此,研究皮瓣坏死的危险因素、评估技术和治疗方法至关重要。

方法

作者使用PubMed、科学网和考克兰图书馆,对2010年1月至2024年8月的相关研究进行了全面检索。检索词包括“自体乳房重建”、“皮瓣坏死”、“危险因素”、“评估”和“治疗”。作者首先筛选标题和摘要,然后由3名研究人员进行详细审查,以确定符合纳入标准的研究。

结果

最终共选择68项研究进行分析。确定的皮瓣坏死危险因素包括吸烟、高龄、肥胖、糖尿病、乳房体积大、既往放疗和腹部手术。各种评估方法(如术前成像、术中血流监测和术后评估)可提高皮瓣存活率。该综述还涵盖了手术治疗策略和非手术干预措施,包括局部伤口护理、高压氧治疗和药物治疗。

结论

本综述强调了全面规划和管理在降低自体乳房重建后皮瓣坏死风险方面的关键作用。有效的术前评估、围手术期监测和特定的术后干预措施可显著降低皮瓣坏死的发生率。

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