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Correction: Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.更正:维多福啶通过靶向二氢乳清酸脱氢酶抑制猪繁殖与呼吸综合征病毒感染。
Vet Res. 2024 Dec 27;55(1):173. doi: 10.1186/s13567-024-01447-y.
2
Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.维地福卢米司抑制猪繁殖与呼吸综合征病毒感染的作用机制是靶向二氢乳清酸脱氢酶。
Vet Res. 2023 Dec 20;54(1):124. doi: 10.1186/s13567-023-01251-0.
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Identification of dihydroorotate dehydrogenase inhibitor, vidofludimus, as a potent and novel inhibitor for influenza virus.鉴定二氢乳清酸脱氢酶抑制剂维地福卢米司他是一种新型有效的流感病毒抑制剂。
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A double-blind, randomized, placebo-controlled phase 2 trial evaluating the selective dihydroorotate dehydrogenase inhibitor vidofludimus calcium in relapsing-remitting multiple sclerosis.一项评估选择性二氢乳清酸脱氢酶抑制剂维地福卢米昔钙在复发缓解型多发性硬化症中的双盲、随机、安慰剂对照 2 期试验。
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Repositioning an Immunomodulatory Drug Vidofludimus as a Farnesoid X Receptor Modulator With Therapeutic Effects on NAFLD.将免疫调节药物维多氟啶重新定位为法尼酯X受体调节剂,对非酒精性脂肪性肝病具有治疗作用。
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Vidofludimus calcium, a next generation DHODH inhibitor for the Treatment of relapsing-remitting multiple sclerosis.维地福卢米单抗钙,一种用于治疗复发缓解型多发性硬化症的新一代二氢乳清酸脱氢酶抑制剂。
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The Selective Oral Immunomodulator Vidofludimus in Patients with Active Rheumatoid Arthritis: Safety Results from the COMPONENT Study.选择性口服免疫调节剂 Vidofludimus 治疗活动期类风湿关节炎患者:COMPONENT 研究的安全性结果。
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Synthesis and Characterization of DHODH Inhibitors Based on the Vidofludimus Scaffold with Pronounced Anti-SARS-CoV-2 Activity.基于 Vidofludimus 支架的 DHODH 抑制剂的合成与表征,具有显著抗 SARS-CoV-2 活性。
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本文引用的文献

1
Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.维地福卢米司抑制猪繁殖与呼吸综合征病毒感染的作用机制是靶向二氢乳清酸脱氢酶。
Vet Res. 2023 Dec 20;54(1):124. doi: 10.1186/s13567-023-01251-0.

Correction: Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.

作者信息

Yang Yuanqi, Gao Yanni, Zhang Lujie, Liu Xing, Sun Yangyang, Bai Juan, Jiang Ping

机构信息

Key Laboratory of Animal Diseases Diagnostic and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.

Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, China.

出版信息

Vet Res. 2024 Dec 27;55(1):173. doi: 10.1186/s13567-024-01447-y.

DOI:10.1186/s13567-024-01447-y
PMID:39731128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11681666/
Abstract
摘要