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超越分类:儿童中一例与链球菌感染相关的自行消退性皮肤粘蛋白病的独特病例。

Beyond Classification: A Unique Case of Self-Resolving Cutaneous Mucinosis Associated With Streptococcal Infection in a Child.

作者信息

Safir Ari, Furman Moran, Gat Andrea, Zemser Valentina, Bergman Reuven, Sprecher Eli, Samuelov Liat, Friedel Nadav

机构信息

Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.

出版信息

Pediatr Dermatol. 2025 May-Jun;42(3):625-630. doi: 10.1111/pde.15856. Epub 2024 Dec 28.

Abstract

A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months. This case represents a unique presentation of a self-resolving cutaneous mucinosis, likely associated with a streptococcal infection.

摘要

一名3岁男孩出现了硬结性皮肤、伴有苔藓化的硬化斑块和淡黄色丘疹的异常组合。组织病理学显示真皮弥漫性黏蛋白沉积,实验室检查显示A组链球菌咽拭子培养阳性且血清抗链球菌溶血素滴度升高。口服阿莫西林10天的疗程使所有皮肤症状在4个月内几乎完全消退。该病例代表了一种自行消退的皮肤黏蛋白病的独特表现,可能与链球菌感染有关。

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