Safir Ari, Furman Moran, Gat Andrea, Zemser Valentina, Bergman Reuven, Sprecher Eli, Samuelov Liat, Friedel Nadav
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Pediatr Dermatol. 2025 May-Jun;42(3):625-630. doi: 10.1111/pde.15856. Epub 2024 Dec 28.
A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months. This case represents a unique presentation of a self-resolving cutaneous mucinosis, likely associated with a streptococcal infection.
一名3岁男孩出现了硬结性皮肤、伴有苔藓化的硬化斑块和淡黄色丘疹的异常组合。组织病理学显示真皮弥漫性黏蛋白沉积,实验室检查显示A组链球菌咽拭子培养阳性且血清抗链球菌溶血素滴度升高。口服阿莫西林10天的疗程使所有皮肤症状在4个月内几乎完全消退。该病例代表了一种自行消退的皮肤黏蛋白病的独特表现,可能与链球菌感染有关。