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[皮肤黏蛋白沉积症]

[Cutaneous mucinosis].

作者信息

Rongioletti F, Rebora A

机构信息

Clinica Dermatologica, Università di Genova, Italie.

出版信息

Ann Dermatol Venereol. 1993;120(1):75-87.

PMID:8338331
Abstract

The cutaneous mucinoses are a heterogeneous group of diseases in which mucin accumulates in the skin or within the hair follicle. We divide the cutaneous mucinoses into two groups: the distinctive cutaneous mucinoses in which the mucin deposit is a distinctive histopathologic feature that manifests as a clinically specific lesion, and the diseases associated with histopathologic mucin deposition as an additional finding. This article deals with the clinical and histopathologic features and the treatment of the distinctive cutaneous mucinoses and updates their classification. They may be divided, according to the microscopic location of mucin, into dermal and follicular mucinoses. The former group includes; lichen myxedematosus, acral persistent papular mucinosis, reticular erythematous mucinosis, scleredema, dysthyroidotic mucinoses (i.e. localized myxedema, generalized myxedema, papular mucinoses associated with thyroid diseases), papular and nodular mucinosis associated with lupus erythematosus, self-healing juvenile cutaneous mucinosis, cutaneous mucinosis of the infancy, cutaneous toxic mucinoses (papular mucinosis of the toxic oil syndrome and of eosinophiliamyalgia syndrome), neuropathia mucinosa cutanea, cutaneous focal mucinosis, mucous cyst (digital and of the oral mucosa), while the latter group includes Pinkus' follicular mucinosis and urticaria-like follicular mucinosis.

摘要

皮肤黏蛋白沉积症是一组异质性疾病,其中黏蛋白在皮肤或毛囊内蓄积。我们将皮肤黏蛋白沉积症分为两组:特异性皮肤黏蛋白沉积症,其中黏蛋白沉积是一种独特的组织病理学特征,表现为临床上特定的损害;以及与组织病理学黏蛋白沉积作为附加表现相关的疾病。本文论述特异性皮肤黏蛋白沉积症的临床和组织病理学特征及治疗方法,并更新其分类。根据黏蛋白在显微镜下的位置,可将其分为真皮黏蛋白沉积症和毛囊黏蛋白沉积症。前一组包括:黏液水肿性苔藓、肢端持续性丘疹性黏蛋白沉积症、网状红斑性黏蛋白沉积症、硬化性水肿、甲状腺功能异常性黏蛋白沉积症(即局限性黏液水肿、全身性黏液水肿、与甲状腺疾病相关的丘疹性黏蛋白沉积症)、与红斑狼疮相关的丘疹性和结节性黏蛋白沉积症、自愈性青少年皮肤黏蛋白沉积症、婴儿期皮肤黏蛋白沉积症、皮肤中毒性黏蛋白沉积症(中毒性油综合征和嗜酸性筋膜炎综合征的丘疹性黏蛋白沉积症)、皮肤神经性黏蛋白沉积症、皮肤局限性黏蛋白沉积症、黏液囊肿(指部和口腔黏膜的),而后一组包括平卡斯毛囊黏蛋白沉积症和荨麻疹样毛囊黏蛋白沉积症。

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