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[内科和心脏病学急诊科的九旬老人:合并症、病程及生存率与年轻患者的比较]

[Nonagenarians on an emergency department for internal medicine and cardiology : Comparison of comorbidities, disease course and survival with younger patients].

作者信息

Sow Lisa-Maria, Stöllberger Claudia, Lazarevic Patrick, Udovica Simon, Weidinger Franz

机构信息

2. Med. Abteilung, Klinik Landstraße, Juchgasse 25, 1030, Wien, Österreich.

Center Wissenschaft, Bundesanstalt Statistik Österreich, Guglgasse 13, 1110, Wien, Österreich.

出版信息

Z Gerontol Geriatr. 2024 Dec 28. doi: 10.1007/s00391-024-02389-y.

Abstract

BACKGROUND

Little is known about how younger and older hospitalized patients differ with respect to reasons for admission, comorbidities, diagnostics, treatment and intercurrent problems.

OBJECTIVE

The aim of the study was to compare the previously named characteristics in the clinical profile of patients > 90 years old (nonagenarians) with a control group of patients 70-75 years old admitted to an emergency hospital department for internal medicine and cardiology.

MATERIAL AND METHOD

The study included all consecutive nonagenarians and gender-matched control patients who were admitted during 2011. The reason for admission, comorbidities, diagnostics, treatment, intercurrent problems and discharge medication were taken from the patient records. Data on 8‑year mortality were obtained by comparison of the death data.

RESULTS

Nonagenarians (n = 117; 81 females) had a mean age of 92 ± 2.5 years and the control patients 72 ± 1.6 years. Nonagenarians were hospitalized more often because of neurological symptoms (19% vs. 7%), suffered more from kidney failure (85% vs. 67%), heart failure (35% vs. 21%), malignancies (29% vs. 8%), dementia (28% vs. 4%) and stroke (15% vs. 6%), developed confusion more often (27% vs. 7%) and fell more often (15% vs. 0%) than control patients. Control patients had a higher body mass index (29 ± 5.3 vs. 24 ± 4.1). Nonagenarians received fewer diagnostic measures (1.6 vs. 2.3), more often intravenous fluid (77% vs. 51%), diuretics (31% vs. 18%) and physiotherapy (24% vs. 8%). Polypharmacy (> 5 medications) in the discharge letter was frequent in both groups (67% vs. 75%). The yearly mortality of the nonagenarians was 27% and of the control group 6%.

CONCLUSION

Acute internal diseases in nonagenarians are frequently manifested with neurological symptoms. In hospitalized nonagenarians, prevention of falls and delirium are of clinical relevance. Polypharmacy is a relevant problem in nonagenarians as well as in control patients.

摘要

背景

关于老年和年轻住院患者在入院原因、合并症、诊断、治疗及并发问题方面的差异,人们了解甚少。

目的

本研究旨在比较90岁以上(非agenarians)患者与70 - 75岁内科及心脏病科急诊住院对照组患者临床资料中的上述特征。

材料与方法

本研究纳入了2011年期间收治的所有连续的非agenarians患者以及性别匹配的对照患者。入院原因、合并症、诊断、治疗、并发问题及出院用药均取自患者病历。通过比较死亡数据获取8年死亡率的数据。

结果

非agenarians患者(n = 117;81名女性)平均年龄为92 ± 2.5岁,对照患者平均年龄为72 ± 1.6岁。非agenarians患者因神经症状住院更为频繁(19% 对7%),肾衰竭(85% 对67%)、心力衰竭(35% 对21%)、恶性肿瘤(29% 对8%)、痴呆(28% 对4%)及中风(15% 对6%)的患病率更高,出现意识模糊(27% 对7%)和跌倒(15% 对0%)的情况也比对照患者更为常见。对照患者的体重指数更高(29 ± 5.3对24 ± 4.1)。非agenarians患者接受的诊断措施较少(1.6对2.3),静脉输液(77% 对51%)、利尿剂(31% 对18%)及物理治疗(24% 对8%)更为常见。两组出院小结中使用多种药物(> 5种药物)的情况都很常见(67% 对75%)。非agenarians患者的年死亡率为27%,对照组为6%。

结论

非agenarians患者的急性内科疾病常表现为神经症状。在住院的非agenarians患者中,预防跌倒和谵妄具有临床意义。使用多种药物在非agenarians患者和对照患者中都是一个相关问题。

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