衰弱可能是老年房颤患者射频导管消融术后复发的一个新的预测因素。
Frailty may be a new predictive factor of recurrence after radiofrequency catheter ablation in elderly atrial fibrillation patients.
作者信息
Lin Hairong, Lin Mei, Li Hong, Sun Dingce
机构信息
Department of Gastroenterology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Changjia Road No.12, Jingzhong District, ZIP Code 621099, Mianyang, Sichuan, China.
Department of Nursing, Tianjin Medical University General Hospital, Anshan Road No.154, Heping District, ZIP Code 300052, Tianjin, China.
出版信息
Geriatr Nurs. 2025 Jan-Feb;61:429-433. doi: 10.1016/j.gerinurse.2024.12.008. Epub 2024 Dec 27.
BACKGROUND
Frailty and atrial fibrillation (AF) outcomes require in-depth, multidimensional investigation. We aim to explore the association between frailty and factors such as hospital stay, quality of life, and recurrence after radiofrequency catheter ablation (RFCA) in elderly patients.
METHODS
We conducted a prospective cohort study involving 195 hospitalized elderly AF patients. The FRAIL scale was used to assess frailty, while the EQ-5D-5L scale evaluated the quality of life. Recurrence status was tracked over a 6-month follow-up period. Survival analysis, linear regression, and logistic regression were employed for data analysis.
RESULTS
The prevalence of frailty among participants was 24.1%. Our findings indicate that frailty is associated with higher recurrence rates after RFCA (p=0.028, OR=2.43), longer hospitalization stay(p=0.034, OR=2.21), and poorer quality of life (p=0.001, β'=-0.287).
CONCLUSION
Early screening and intervention for frail elderly AF patients should be prioritized to enhance their prognosis and quality of life.
背景
衰弱与房颤结局需要进行深入的多维度研究。我们旨在探讨老年患者衰弱与住院时间、生活质量以及射频导管消融术（RFCA）后复发等因素之间的关联。
方法
我们进行了一项前瞻性队列研究，纳入了195例住院老年房颤患者。采用衰弱量表评估衰弱程度，采用EQ-5D-5L量表评估生活质量。在6个月的随访期内跟踪复发情况。采用生存分析、线性回归和逻辑回归进行数据分析。
结果
参与者中衰弱的患病率为24.1%。我们的研究结果表明，衰弱与RFCA后较高的复发率（p=0.028，OR=2.43）、较长的住院时间（p=0.034，OR=2.21）以及较差的生活质量（p=0.001，β'=-0.287）相关。
结论
应优先对衰弱的老年房颤患者进行早期筛查和干预，以改善其预后和生活质量。
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