Shaughnessy Lynn W, Weintraub Sandra
Beth Israel Deaconess Medical Center, Cognitive Neurology Unit, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.
Alzheimers Dement. 2025 Jan;21(1):e14363. doi: 10.1002/alz.14363. Epub 2024 Dec 28.
The Alzheimer's Association convened a Diagnostic Evaluation, Testing, Counseling and Disclosure Clinical Practice Guideline workgroup to help combat the major global health challenges surrounding the timely detection, accurate diagnosis, and appropriate disclosure of mild cognitive impairment (MCI) or dementia due to Alzheimer's disease (AD) or other diseases that cause these types of cognitive-behavioral disorders. The newly published clinical practice guidelines are proposed as a structured approach to evaluation. The purpose of the present article is to provide a clinical perspective on the use of neuropsychology within the new framework and practice guidelines outlined under the Diagnostic Evaluation, Testing, Counseling and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD) recommendations for primary care and specialty care. Neuropsychological evaluation is a critical component in supporting early and accurate diagnosis and staging, characterizing the clinical profile, assessing trajectory over time, and providing recommendations specifically tailored to the individual and their care team. HIGHLIGHTS: Reviews the neuropsychological evaluation component of the new framework and clinical practice guidelines outlined under the Alzheimer's Association clinical practice guidelines for the Diagnostic Evaluation, Testing, Counseling and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD). Examines the utility of neuropsychological evaluation in the assessment of Alzheimer's Disease and Related Disorders (ADRD). Supports a basis for neuropsychology in early and accurate diagnosis and staging, characterizing the clinical profile, assessing trajectory over time, and providing recommendations specifically tailored to the individual and their care team.
阿尔茨海默病协会召集了一个诊断评估、检测、咨询与披露临床实践指南工作组，以应对围绕阿尔茨海默病（AD）或其他导致此类认知行为障碍的疾病所引发的轻度认知障碍（MCI）或痴呆症的及时检测、准确诊断和适当披露的重大全球健康挑战。新发布的临床实践指南被提议作为一种结构化的评估方法。本文的目的是就初级保健和专科护理的疑似阿尔茨海默病及相关疾病的诊断评估、检测、咨询与披露（DETeCD - ADRD）建议所概述的新框架和实践指南内神经心理学的应用提供临床视角。神经心理学评估是支持早期准确诊断和分期、描述临床特征、评估随时间变化的病程轨迹以及提供针对个体及其护理团队的具体建议的关键组成部分。要点：回顾阿尔茨海默病协会临床实践指南中关于疑似阿尔茨海默病及相关疾病的诊断评估、检测、咨询与披露（DETeCD - ADRD）所概述的新框架和临床实践指南的神经心理学评估部分。探讨神经心理学评估在阿尔茨海默病及相关疾病（ADRD）评估中的效用。支持神经心理学在早期准确诊断和分期、描述临床特征、评估随时间变化的病程轨迹以及提供针对个体及其护理团队的具体建议方面的依据。
