Komatsu M, Yamamoto K, Kawashima T, Migita S
J Immunol. 1985 Apr;134(4):2607-9.
Genetic deficiency of the alpha-gamma-subunit of the eighth complement component (C8 alpha-gamma) was found in a strain of the New Zealand White rabbit. The serum of this deficient rabbit lacked the immunochemical and functional alpha-gamma-subunit of C8. Mating tests indicate that the C8 alpha-gamma deficiency is transmitted as a simple autosomal recessive trait with the following physiologic characteristics. The body weight at the first week of life, mature weight, and litter size of the deficient animals were smaller than those of heterozygous and normal ones. In addition, survival rates for the first 3 mo of life of the deficient animals tended to be lower than those of heterozygous and normal littermates.
在新西兰白兔的一个品系中发现了第八补体成分（C8α-γ）的α-γ亚基的基因缺陷。这只缺陷兔的血清缺乏C8的免疫化学和功能性α-γ亚基。交配试验表明，C8α-γ缺陷作为一种简单的常染色体隐性性状遗传，具有以下生理特征。缺陷动物出生第一周的体重、成熟体重和产仔数均低于杂合子和正常动物。此外，缺陷动物出生后前3个月的存活率往往低于杂合子和正常同窝仔兔。
