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国产鼻腔填塞海绵与进口鼻孑L海绵在鼻窦切开术后护理中的临床对比研究

[A clinical comparative study of domestic nasal packing sponge and imported nasopore sponge in post-sinusotomy care].

作者信息

Liu Shengyang, Li Tao, Sun Shujuan, Yu Peng, Tu Yanyi, Xiao Limian, Wan Yuzhu, Shi Li

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,Shandong Prpvincial ENT HosPital,Shandong University,Jinan,250000,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2025 Jan;39(1):71-76. doi: 10.13201/j.issn.2096-7993.2025.01.015.

Abstract

This study aims to investigate the differences in hemostatic efficacy and patient comfort between an innovative domestically produced biodegradable nasal packing sponge and a traditional absorbent sponge following endoscopic nasal surgery. A prospective, randomized controlled trial design was utilized, including 30 patients who were divided into two groups according to random allocation, each receiving one of the two types of nasal packing. The study assessed the hemostatic efficacy, comfort, and safety of the materials by comparing the rates of no bleeding within 24 hours after packing, re-bleeding rates after 48 hours, pain ratings in the head and nasal areas, scores on a visual analog scale for nasal ocular symptoms, and safety indicators between the two groups. The rates of no bleeding within 24 hours post-packing were 73.33% for both the experimental and control groups, with a no-bleeding rate of 100% after 48 hours in both groups. The pain rating in the head and nasal areas at various times post-packing was Grade Ⅰ(100%) in both groups, with no statistically significant difference(=1.000). The experimental groups sneezing score on the day of packing was(0.73±1.03), lower than the control groups(2.27±1.67), (=0.007); after 48 hours, the experimental groups sneezing score was(0.67±0.98), also lower than the control groups(1.67±1.18), (=0.019). There was no significant difference between the two groups in the Lund-Kennedy scoring during endoscopic examinations at the screening period, 7 days, 1 month, and 3 months post-packing(>0.05). Laboratory tests for other examination indicators were normal in both groups. The innovative domestically produced biodegradable nasal packing sponge not only provides hemostatic efficacy comparable to imported materials but also significantly improves patient comfort after surgery. It represents an economical and effective choice for nasal packing materials.

摘要

本研究旨在探讨国产新型可生物降解鼻腔填塞海绵与传统吸收性海绵在内镜鼻窦手术后止血效果及患者舒适度方面的差异。采用前瞻性随机对照试验设计,纳入30例患者,根据随机分配分为两组,每组接受两种类型鼻腔填塞物中的一种。通过比较两组填塞后24小时内无出血率、48小时后再出血率、头面部及鼻腔疼痛评分、鼻眼部症状视觉模拟量表评分及安全指标,评估材料的止血效果、舒适度和安全性。实验组和对照组填塞后24小时内无出血率均为73.33%,两组48小时后无出血率均为100%。两组填塞后不同时间头面部及鼻腔疼痛评分为Ⅰ级(100%),差异无统计学意义(=1.000)。实验组填塞当天打喷嚏评分为(0.73±1.03),低于对照组(2.27±1.67),(=0.007);48小时后,实验组打喷嚏评分为(0.67±0.98),也低于对照组(1.67±1.18),(=0.019)。两组在填塞后筛查期、7天、1个月及3个月内镜检查时的Lund-Kennedy评分差异无统计学意义(>0.05)。两组其他检查指标实验室检查均正常。国产新型可生物降解鼻腔填塞海绵不仅止血效果与进口材料相当,还能显著提高术后患者舒适度。它是鼻腔填塞材料的一种经济有效的选择。

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本文引用的文献

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[Strategy of the diagnosis and treatment for epistaxis and guideline for clinical application of MasterPillar].[鼻出血诊疗策略与MasterPillar临床应用指南]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Jul;37(7):519-523. doi: 10.13201/j.issn.2096-7993.2023.07.003.
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Designing novel bioconjugates of hydroxyethyl cellulose and salicylates for potential pharmaceutical and pharmacological applications.
Int J Biol Macromol. 2017 Oct;103:441-450. doi: 10.1016/j.ijbiomac.2017.05.061. Epub 2017 May 16.
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Advances in Absorbable Biomaterials and Nasal Packing.可吸收生物材料与鼻腔填塞的进展
Otolaryngol Clin North Am. 2017 Jun;50(3):545-563. doi: 10.1016/j.otc.2017.01.006. Epub 2017 Mar 9.
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Nasal dressings after endoscopic sinus surgery: what and why?鼻内镜鼻窦手术后的鼻腔敷料:用什么及为何用?
Curr Opin Otolaryngol Head Neck Surg. 2010 Feb;18(1):44-8. doi: 10.1097/MOO.0b013e3283346f36.

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