Solanki Sohan Lal, Sharma Jyoti
Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, MH 400012, India.
Department of Anaesthesiology, All India Institute of Medical Sciences, Bathinda 151001, India.
World J Gastrointest Surg. 2024 Dec 27;16(12):3663-3665. doi: 10.4240/wjgs.v16.i12.3663.
We present an editorial on an article that highlights the benefits of dexmedetomidine (Dex) in colon cancer surgeries, which have been thoroughly investigated in the referenced publication involving 117 subjects. Of these patients, 59 (group A) received Dex before anesthesia induction, while 58 (group B) received normal saline. Group A patients demonstrated several advantages over Group B, including lower propofol and remifentanil requirements, improved cerebral oxygenation as measured by regional cerebral oxygen saturation, better hemodynamic stability, and reduced incidence of postoperative cognitive dysfunction. In addition to its sedative and analgesic effects, Dex decreases the need for other anesthetic agents and enhances cerebral oxygenation in elderly patients undergoing colorectal surgery. The literature also supports the anti-inflammatory properties of Dex, which can reduce surgical stress and improve postoperative recovery in cancer patients. This editorial focuses on the various benefits of Dex, particularly its role in maintaining hemodynamic stability and facilitating early recovery in cancer patients.
我们发表一篇关于一篇文章的社论，该文章强调了右美托咪定（Dex）在结肠癌手术中的益处，这些益处在涉及117名受试者的参考文献中得到了充分研究。在这些患者中，59名（A组）在麻醉诱导前接受了Dex，而58名（B组）接受了生理盐水。A组患者相对于B组表现出几个优势，包括丙泊酚和瑞芬太尼需求量更低、通过局部脑氧饱和度测量的脑氧合改善、更好的血流动力学稳定性以及术后认知功能障碍发生率降低。除了其镇静和镇痛作用外，Dex还减少了老年结直肠手术患者对其他麻醉剂的需求并增强了脑氧合。文献也支持Dex的抗炎特性，其可减轻手术应激并改善癌症患者的术后恢复。这篇社论重点关注Dex的各种益处，特别是其在维持癌症患者血流动力学稳定性和促进早期恢复方面的作用。
