Xie Fei-Fei, Qian Su-Ting, Zhao Hao-Yu, Liu Qing-Sheng
Department of Digestive, Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Hangzhou 310007, Zhejiang Province, China.
Science and Education Section, Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Hangzhou 310007, Zhejiang Province, China.
World J Gastrointest Surg. 2024 Dec 27;16(12):3881-3886. doi: 10.4240/wjgs.v16.i12.3881.
Gastric cancer (GC) metastasis is the main cause of poor prognosis for GC patients. In recent years, breakthroughs in immunotherapy have been made in the treatment of many kinds of cancers, providing new hope for patients with GC metastasis. This paper reviews the mechanism of immunotherapy in GC metastasis and its clinical application, and discusses and compares the research and efficacy of immunotherapy in patients with liver metastasis, lung metastasis, peritoneal metastasis and lymph node metastasis of GC. This study explores the challenges and future development directions of immunotherapy, and provides a theoretical basis and clinical guidance for the precise treatment of patients with GC metastasis.
胃癌（GC）转移是GC患者预后不良的主要原因。近年来，免疫疗法在多种癌症的治疗中取得了突破，为GC转移患者带来了新希望。本文综述了免疫疗法在GC转移中的作用机制及其临床应用，并对GC肝转移、肺转移、腹膜转移和淋巴结转移患者的免疫疗法研究及疗效进行了讨论和比较。本研究探讨了免疫疗法面临的挑战和未来发展方向，为GC转移患者的精准治疗提供理论依据和临床指导。
