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Docetaxel-induced lung injury.多西他赛诱导的肺损伤。
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本文引用的文献

1
Docetaxel-induced interstitial lung disease among patients with breast cancer: a case series and review of literature.多西他赛诱导的乳腺癌患者间质性肺疾病:病例系列及文献综述
Respirol Case Rep. 2021 Jun 13;9(7):e00802. doi: 10.1002/rcr2.802. eCollection 2021 Jul.
2
Docetaxel-related interstitial pneumonitis.多西他赛相关的间质性肺炎。
Ther Clin Risk Manag. 2015 Dec 9;11:1813-6. doi: 10.2147/TCRM.S90488. eCollection 2015.
3
Pneumonitis and pulmonary fibrosis in a patient receiving adjuvant docetaxel and cyclophosphamide for stage 3 breast cancer: a case report and literature review.一名接受多西他赛和环磷酰胺辅助治疗的III期乳腺癌患者发生肺炎和肺纤维化:病例报告及文献综述
J Med Case Rep. 2012 Nov 30;6:413. doi: 10.1186/1752-1947-6-413.
4
Docetaxel-induced interstitial pneumonitis following non-small-cell lung cancer treatment.多西他赛治疗非小细胞肺癌后引起的间质性肺炎。
Clin Transl Oncol. 2007 Sep;9(9):578-81. doi: 10.1007/s12094-007-0106-4.
5
A randomized trial of different docetaxel schedules in non-small cell lung cancer patients who failed previous platinum-based chemotherapy.一项针对先前铂类化疗失败的非小细胞肺癌患者采用不同多西他赛给药方案的随机试验。
Chest. 2006 Apr;129(4):1031-8. doi: 10.1378/chest.129.4.1031.
6
Fatal pulmonary fibrosis induced by paclitaxel: a case report and review of the literature.紫杉醇诱导的致命性肺纤维化:一例病例报告及文献复习
Int J Gynecol Cancer. 2006 Jan-Feb;16 Suppl 1:391-3. doi: 10.1111/j.1525-1438.2006.00222.x.
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Severe interstitial pneumonitis associated with docetaxel administration.与多西他赛给药相关的严重间质性肺炎。
Cancer. 2002 Feb 1;94(3):847-53. doi: 10.1002/cncr.10263.
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Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer.
Semin Oncol. 2001 Aug;28(4 Suppl 15):3-7. doi: 10.1016/s0093-7754(01)90148-4.
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Paclitaxel-induced acute bilateral pneumonitis.紫杉醇诱导的急性双侧肺炎。
Ann Pharmacother. 1997 Dec;31(12):1471-4. doi: 10.1177/106002809703101205.
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Docetaxel.多西他赛
J Clin Oncol. 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643.

多西他赛诱导的肺损伤。

Docetaxel-induced lung injury.

作者信息

Vasan Amit Singh, Chowdhary Gurjeet Singh, Pandey Indramani, Garg Yadvir, Soneji Dharmesh

机构信息

Graded Specialist (Pulmonary Medicine), Command Hospital (Western Command), Chandimandir, Haryana, India.

Senior Advisor (Medical Oncology), Command Hospital (Western Command), Chandimandir, Haryana, India.

出版信息

Med J Armed Forces India. 2024 Dec;80(Suppl 1):S275-S278. doi: 10.1016/j.mjafi.2023.02.002. Epub 2023 Apr 10.

DOI:10.1016/j.mjafi.2023.02.002
PMID:39734894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11670627/
Abstract

Docetaxel is a chemotherapeutic agent commonly used against breast cancer, nonsmall cell lung cancer, gastric, prostate, head and neck cancer. Docetaxel- or taxane-induced interstitial lung disease (ILD) remains a relatively rare reported adverse event. Although rare, this complication remains an important event to identify and it carries a high mortality. We reported the case series of three patients who had pulmonary toxicity after docetaxel administration. Although literature has described patients progressing to respiratory failure and intubation, our patients responded well to steroid treatment and discontinued docetaxel administration.

摘要

多西他赛是一种常用于治疗乳腺癌、非小细胞肺癌、胃癌、前列腺癌、头颈癌的化疗药物。多西他赛或紫杉烷诱导的间质性肺病(ILD)仍然是一种报道相对较少的不良事件。尽管罕见,但这种并发症仍然是一个需要识别的重要事件,并且具有很高的死亡率。我们报告了3例多西他赛给药后出现肺部毒性的病例系列。虽然文献中描述了患者进展为呼吸衰竭和插管,但我们的患者对类固醇治疗反应良好,并停止了多西他赛给药。