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应对环境压力:为何是时候转向抑郁症的新疗法了?

Dealing With Environmental Stress: Why Is It Time to Move Towards a New Approach to Depression?

作者信息

Russo Claudio

机构信息

Health and Technology, Stress Management and Therapy Clinic, Naples, ITA.

出版信息

Cureus. 2024 Nov 27;16(11):e74566. doi: 10.7759/cureus.74566. eCollection 2024 Nov.

DOI:10.7759/cureus.74566
PMID:39734973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11672221/
Abstract

Depression is a complex mental health condition characterized by persistent sadness, loss of interest, and a range of cognitive, emotional, and behavioral symptoms. It can be acute or chronic and is often influenced by a combination of genetic, biological, psychological, and social factors. According to transnational estimates of prevalence, depressive symptoms represent the most concerning challenge to mental health across cultures and beyond geographical borders. There are growing public health concerns that depression is leading to an increase in suicide rates, while causing diversity, uncertainty of treatment options and cultural stigma. The current trends in life expectancy make depression a great challenge for global health, while there are unsolved care problems on how to implement adequate responses and treatment at local and global levels. The main purpose of this article is to highlight why an integrated path to care is more critical than ever before. The role of biomedical sciences and modern psychology is therefore discussed in terms of how developing our knowledge may better help us to support those with depression, and to inspire new research methods in primary and secondary care.

摘要

抑郁症是一种复杂的心理健康状况,其特征为持续的悲伤、兴趣丧失以及一系列认知、情绪和行为症状。它可以是急性的或慢性的,并且常常受到遗传、生物、心理和社会因素的综合影响。根据跨国患病率估计,抑郁症状是跨文化和超越地理边界的心理健康方面最令人担忧的挑战。越来越多的公共卫生问题表明,抑郁症导致自杀率上升,同时造成治疗选择的多样性、不确定性以及文化污名化。当前预期寿命的趋势使抑郁症成为全球健康的巨大挑战,而在如何在地方和全球层面实施适当应对措施和治疗方面仍存在未解决的护理问题。本文的主要目的是强调为什么综合护理途径比以往任何时候都更加关键。因此,将从发展我们的知识如何更好地帮助我们支持抑郁症患者以及激发初级和二级护理中的新研究方法的角度,讨论生物医学科学和现代心理学的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd7e/11672221/78f444d52ecf/cureus-0016-00000074566-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd7e/11672221/4185fe4e0699/cureus-0016-00000074566-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd7e/11672221/78f444d52ecf/cureus-0016-00000074566-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd7e/11672221/4185fe4e0699/cureus-0016-00000074566-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd7e/11672221/78f444d52ecf/cureus-0016-00000074566-i02.jpg

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JAMA. 2023 Jun 20;329(23):2068-2085. doi: 10.1001/jama.2023.7787.
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Childhood adversity, mental health, and oxidative stress: A pilot study.儿童逆境、心理健康和氧化应激:一项初步研究。
PLoS One. 2019 Apr 26;14(4):e0215085. doi: 10.1371/journal.pone.0215085. eCollection 2019.
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Depression sum-scores don't add up: why analyzing specific depression symptoms is essential.抑郁总分并不等同于各症状得分总和:为何分析特定抑郁症状至关重要。
BMC Med. 2015 Apr 6;13:72. doi: 10.1186/s12916-015-0325-4.
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Grand challenges in global mental health: integration in research, policy, and practice.全球精神卫生领域的重大挑战:研究、政策和实践的融合。
PLoS Med. 2013;10(4):e1001434. doi: 10.1371/journal.pmed.1001434. Epub 2013 Apr 30.
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The epidemiology of depression across cultures.跨文化抑郁症的流行病学。
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