Onobun Daniel E, Orji Chijioke, Ojo Ethel O, Adebisi Ajibola A, Igbokwe Kenechukwu, Sehmar Rajinder, Ononye Reginald, Aksaray Olgun, Oputa Stephen, Nmereole Chidera S
Orthopedics and Trauma, Warwick Hospital, South Warwickshire University NHS Foundation Trust, Warwick, GBR.
Orthopedics, Liverpool University Hospitals Foundation Trust, Liverpool, GBR.
Cureus. 2024 Nov 29;16(11):e74718. doi: 10.7759/cureus.74718. eCollection 2024 Nov.
This systematic review and meta-analysis evaluate the comparative outcomes of conservative management versus surgical intervention for anterior cruciate ligament (ACL) injuries. A comprehensive search of PubMed, Cochrane Library, Web of Science, SPORTDiscus, and Google Scholar focused on studies published between 2010 and 2024. Data synthesis employed both thematic analysis for qualitative data and meta-analysis for quantitative outcomes. Key findings indicate that conservative management yields lower reinjury rates and higher quality of life (QoL) scores (64.6 vs. 57.1) compared to surgical intervention, though differences were not statistically significant (p = 0.1483). Both strategies demonstrated comparable return-to-sport (RTS) rates. Meta-regression analysis revealed that longer follow-up durations positively influenced outcomes (p = 0.0288). The average complication rate was 49.83 per study (CI: 25.84-73.82), underscoring significant risks associated with both approaches. Conservative management shows promise as an initial treatment option for certain ACL injuries, particularly regarding reinjury prevention and QoL improvements. However, surgical intervention remains crucial for specific cases requiring enhanced knee stability. The results underscore the importance of individualized treatment planning, long-term follow-up, and further standardization of outcome measures in future research.
本系统评价和荟萃分析评估了前交叉韧带(ACL)损伤保守治疗与手术干预的比较结果。对PubMed、Cochrane图书馆、科学网、SPORTDiscus和谷歌学术进行了全面检索,重点关注2010年至2024年发表的研究。数据综合采用了定性数据的主题分析和定量结果的荟萃分析。主要研究结果表明,与手术干预相比,保守治疗的再损伤率更低,生活质量(QoL)得分更高(64.6对57.1),尽管差异无统计学意义(p = 0.1483)。两种策略的运动恢复(RTS)率相当。荟萃回归分析显示,更长的随访时间对结果有积极影响(p = 0.0288)。每项研究的平均并发症发生率为49.83(CI:25.84 - 73.82),强调了两种方法都存在重大风险。保守治疗对于某些ACL损伤显示出作为初始治疗选择的前景,特别是在预防再损伤和改善生活质量方面。然而,手术干预对于需要增强膝关节稳定性的特定病例仍然至关重要。结果强调了个性化治疗计划、长期随访以及未来研究中结果测量进一步标准化的重要性。