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一名类风湿关节炎患者的结核性指炎:病例报告

Tuberculosis Dactylitis in a Patient With Rheumatoid Arthritis: A Case Report.

作者信息

Pinto Andre, Pereira Joaquim, Caneira Francisco, Garcao Duarte, Rosa Bruno

机构信息

Plastic and Reconstructive Surgery, Hospital de Santa Maria, Unidade Local de Saúde Santa Maria (ULSSM), Lisbon, PRT.

Rheumatology, Hospital de Santa Maria, Unidade Local de Saúde Santa Maria (ULSSM), Lisbon, PRT.

出版信息

Cureus. 2024 Nov 27;16(11):e74569. doi: 10.7759/cureus.74569. eCollection 2024 Nov.

Abstract

Tuberculosis (TB) dactylitis of the hand is a rare and challenging pathology, requiring positive bacterial identification through culture or biopsy for diagnosis. Treatment is also challenging, although it typically yields an excellent response to long-term tuberculostatic therapy. We describe a case of osteoarticular tuberculous dactylitis in a 36-year-old woman with rheumatoid arthritis (RA) and a history of lymphoma. The suspicion arose from an insidious, painless swelling of the proximal interphalangeal joint of the second digit of the right hand in a patient undergoing methotrexate treatment for RA. Under a long-term anti-TB multi-drug regimen, the patient's signs and symptoms progressively improved, and hand function was nearly fully restored. The authors discuss the diagnostic and surgical treatment challenges encountered in plastic and reconstructive surgery care.

摘要

手部结核性指炎是一种罕见且具有挑战性的病症,需要通过培养或活检进行细菌鉴定阳性才能确诊。治疗也颇具挑战性,尽管通常对长期抗结核治疗反应良好。我们描述了一例36岁患有类风湿关节炎(RA)且有淋巴瘤病史的女性的骨关节结核性指炎病例。怀疑源于一名正在接受甲氨蝶呤治疗RA的患者右手第二指近端指间关节出现隐匿性、无痛性肿胀。在长期抗结核多药治疗方案下,患者的体征和症状逐渐改善,手部功能几乎完全恢复。作者讨论了整形和重建外科护理中遇到的诊断和手术治疗挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a16/11672220/f6f4bbdb3ecf/cureus-0016-00000074569-i01.jpg

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