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良性黄斑黄点病变:一组近期发现的黄斑表型患者病例系列

Benign Yellow Dot Maculopathy: A Case Series of Patients With a Recently Discovered Macular Phenotype.

作者信息

Santos Miguel, Oliveira Nuno, Baptista Margarida, Arede Pedro, Marques João Pedro, Vaz-Pereira Sara

机构信息

Department of Ophthalmology, Unidade Local de Saúde (ULS) Santa Maria, Lisbon, PRT.

Department of Ophthalmology, Faculdade de Medicina da Universidade de Lisboa, Lisbon, PRT.

出版信息

Cureus. 2024 Nov 28;16(11):e74652. doi: 10.7759/cureus.74652. eCollection 2024 Nov.

DOI:10.7759/cureus.74652
PMID:39735063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11681434/
Abstract

Benign yellow dot maculopathy (BYDM) is a recently described rare, asymptomatic, early onset, and non-progressive macular phenotype. It is characterized by the presence of multiple white-yellow dots encircling the fovea, which are hyperautofluorescent on fundus autofluorescence. Here, we expand on the few reports available by presenting a case series of five Portuguese patients with clinical BYDM phenotype and congruent multimodal imaging, including the second reported unilateral case. All five patients were female, with a mean age of 31 ± 16 years and mean visual acuity of 0.04 logMAR (logarithm of the minimum angle of resolution), which remained stable throughout long-term follow-up.

摘要

良性黄斑黄点病变(BYDM)是一种最近被描述的罕见、无症状、早发性且非进行性的黄斑表型。其特征是在黄斑中心凹周围存在多个白黄色斑点,这些斑点在眼底自发荧光检查中表现为高自发荧光。在此,我们通过展示一组五例具有临床BYDM表型且多模态成像一致的葡萄牙患者病例系列(包括第二例报道的单侧病例),对现有的少数报告进行补充。所有五例患者均为女性,平均年龄为31±16岁,平均视力为0.04 logMAR(最小分辨角对数),在长期随访中视力保持稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/fa7042134ed6/cureus-0016-00000074652-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/6facac76ab03/cureus-0016-00000074652-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/13014241a820/cureus-0016-00000074652-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/542985a503bd/cureus-0016-00000074652-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/fa7042134ed6/cureus-0016-00000074652-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/6facac76ab03/cureus-0016-00000074652-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/13014241a820/cureus-0016-00000074652-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/542985a503bd/cureus-0016-00000074652-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1802/11681434/fa7042134ed6/cureus-0016-00000074652-i05.jpg

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引用本文的文献

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Extended phenotypic spectrum of benign yellow dot maculopathy.良性黄斑黄点病变的扩展表型谱
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本文引用的文献

1
Benign yellow-dot maculopathy: case report and review of the literature.良性黄斑黄点病变:病例报告及文献综述
Can J Ophthalmol. 2023 Aug;58(4):e191-e194. doi: 10.1016/j.jcjo.2023.01.002. Epub 2023 Jan 23.
2
Multimodal Imaging for Benign Yellow Dot Maculopathy.良性黄斑黄点病变的多模态成像
Ophthalmol Retina. 2022 Apr;6(4):307. doi: 10.1016/j.oret.2021.12.020.
3
Unilateral benign yellow dot maculopathy.单侧良性黄斑黄点病变。
Am J Ophthalmol Case Rep. 2021 Mar 11;22:101068. doi: 10.1016/j.ajoc.2021.101068. eCollection 2021 Jun.
4
Multimodal imaging of benign yellow dot maculopathy.良性黄斑黄点病变的多模态成像
Ophthalmic Genet. 2019 Apr;40(2):135-140. doi: 10.1080/13816810.2019.1589529. Epub 2019 Apr 3.
5
Benign yellow dot maculopathy.良性黄斑黄点病变
Am J Ophthalmol Case Rep. 2018 Jan 28;10:13-15. doi: 10.1016/j.ajoc.2018.01.040. eCollection 2018 Jun.
6
Benign Yellow Dot Maculopathy: A New Macular Phenotype.良性黄斑黄点病变:一种新的黄斑表型。
Ophthalmology. 2017 Jul;124(7):1004-1013. doi: 10.1016/j.ophtha.2017.02.026. Epub 2017 Mar 31.
7
Spectral-domain optical coherence tomography of white dot fovea.白点状黄斑的光谱域光学相干断层扫描
Arch Ophthalmol. 2012 Dec;130(12):1603-5. doi: 10.1001/archophthalmol.2012.2529.