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推进炎症性肠病的早期诊断:呼吁加大力度。

Advancing early diagnosis of inflammatory bowel disease: A call for enhanced efforts.

作者信息

He Shu-Bei, Hu Bing

机构信息

Department of Gastroenterology and Hepatology/Medical Engineering Integration Laboratory of Digestive Endoscopy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

出版信息

World J Gastroenterol. 2024 Dec 28;30(48):5191-5193. doi: 10.3748/wjg.v30.i48.5191.

Abstract

The diagnosis of inflammatory bowel disease (IBD) is complicated by its nonspecific clinical presentation and the limited accuracy of existing biomarker tests, frequently resulting in significant delays from the time of symptom onset to the achievement of a definitive diagnosis. Thus, improving the early identification of IBD remains a crucial focus for gastroenterologists. Blüthner innovatively utilized medical data from German IBD patients to investigate risk factors contributing to these diagnostic delays. However, certain methodological limitations in the study have impacted data extraction and interpretation, underscoring the need for more comprehensive analyses to validate these findings.

摘要

炎症性肠病(IBD)的诊断因临床表现不具特异性以及现有生物标志物检测准确性有限而变得复杂,常常导致从症状出现到确诊的时间出现显著延迟。因此,改善IBD的早期识别仍是胃肠病学家的关键关注点。布吕特纳创新性地利用德国IBD患者的医学数据来研究导致这些诊断延迟的风险因素。然而,该研究中存在的某些方法学局限性影响了数据提取和解读,凸显了进行更全面分析以验证这些发现的必要性。

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本文引用的文献

1
Diagnostic delay in inflammatory bowel diseases in a German population.炎症性肠病的德国人群中的诊断延误。
World J Gastroenterol. 2024 Aug 7;30(29):3465-3478. doi: 10.3748/wjg.v30.i29.3465.
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The overlap between irritable bowel syndrome and organic gastrointestinal diseases.肠易激综合征与器质性胃肠道疾病的重叠。
Lancet Gastroenterol Hepatol. 2021 Feb;6(2):139-148. doi: 10.1016/S2468-1253(20)30212-0. Epub 2020 Nov 13.
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Differentiating Crohn's disease from intestinal tuberculosis.鉴别克罗恩病与肠结核。
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