中国西北老年社区居民中多种疾病与睡眠质量和时长的横断面关联

The Cross-Sectional Association Between Multimorbidity and Sleep Quality and Duration Among the Elderly Community Dwellers in Northwest China.

作者信息

Nuermaimaiti Qiaolifanayi, Heizhati Mulalibieke, Luo Qin, Li Nanfang, Gan Lin, Yao Ling, Yang Wenbo, Li Mei, Li Xiufang, Aierken Xiayire, Hong Jing, Wang Hui, Liu Miaomiao, Maitituersun Adalaiti, Nusufujiang Aketilieke, Cai Li

机构信息

Hypertension Center of People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, 830001, People's Republic of China.

Xinjiang Hypertension Institute, Urumqi, Xinjiang, 830001, People's Republic of China.

出版信息

Nat Sci Sleep. 2024 Dec 25;16:2217-2230. doi: 10.2147/NSS.S497036. eCollection 2024.

DOI:10.2147/NSS.S497036

PMID:39735384

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11682665/

Abstract

BACKGROUND

Multimorbidity, defined as the coexistence of two or more chronic diseases, is highly prevalent among the elderly population and is associated with adverse outcomes. However, little is known about its relationship with sleep issues, particularly in this demographic. Therefore, this study aimed to investigate its association with sleep quality and duration among the elderly.

METHODS

This cross-sectional study was conducted in Emin County, Xinjiang, China, which included a population aged 60 years and above. We employed the Pittsburgh Sleep Quality Index (PSQI) score to assess sleep quality and duration. Multimorbidity was determined through self-reports, physical examination, blood tests, and imaging. Logistic regression analyses were used to explore the association between multimorbidity and sleep patterns, adjusting for confounders.

RESULTS

A total of 8205 elderly participants were included, of whom 66.8% suffered from multimorbidity. Participants with multimorbidity exhibited higher total PSQI scores [6 (3,9)], and a higher percentage of poor sleep quality (50.6%), compared to those without multimorbidity. Multimorbidity was significantly associated with the presence of poor sleep quality (OR = 1.27, 95% CI: 1.14-1.41, P < 0.001) before and after adjusting for confounders. The risk of having poor sleep quality significantly increased as the number of multimorbidities increased. The OR (95% CI) values were 1.16 (1.02,1.32) for two diseases, 1.54 (1.26,1.90) for ≥5 diseases. In the adjusted model for total participants, having four diseases (OR = 1.26, 95% CI: 1.05-1.51, p = 0.013) and five or more diseases (OR = 1.29, 95% CI: 1.03-1.61, p = 0.029) were associated with shorter sleep duration. Furthermore, those with five or more diseases associated with longer sleep duration (OR = 1.40, 95% CI: 1.00-1.95, p = 0.057).

CONCLUSION

There is a significant association between multimorbidity and poor sleep quality in older community dwellers, which may provide clues for disease prevention.

摘要

背景

多病共存被定义为两种或更多种慢性病同时存在，在老年人群中极为普遍，且与不良后果相关。然而，对于其与睡眠问题的关系，尤其是在这一人群中的关系，人们了解甚少。因此，本研究旨在调查其与老年人睡眠质量和睡眠时间的关联。

方法

本横断面研究在中国新疆额敏县进行，纳入了60岁及以上的人群。我们采用匹兹堡睡眠质量指数（PSQI）评分来评估睡眠质量和睡眠时间。通过自我报告、体格检查、血液检查和影像学检查来确定多病共存情况。采用逻辑回归分析来探讨多病共存与睡眠模式之间的关联，并对混杂因素进行校正。

结果

共纳入8205名老年参与者，其中66.8%患有多病共存。与无多病共存的参与者相比，患有多病共存的参与者PSQI总分更高[6（3，9）]，睡眠质量差的比例更高（50.6%）。在校正混杂因素前后，多病共存与睡眠质量差显著相关（OR = 1.27，95%CI：1.14 - 1.41，P < 0.001）。随着多病共存疾病数量的增加，睡眠质量差的风险显著增加。两种疾病的OR（95%CI）值为1.16（1.02，1.32），≥5种疾病的OR（95%CI）值为1.54（1.26，1.90）。在所有参与者的校正模型中，患有四种疾病（OR = 1.26，95%CI：1.05 - 1.51，p = 0.013）和五种或更多种疾病（OR = 1.29，95%CI：1.03 - 1.61，p = 0.029）与睡眠时间缩短相关。此外，患有五种或更多种疾病的参与者与睡眠时间延长相关（OR = 1.40，95%CI：1.00 - 1.95，p = 0.057）。