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脑干出血合并肺炎疑难病例的抗感染治疗分析

Analysis of anti-infective therapy in a challenging case of brainstem hemorrhage complicated with pneumonia.

作者信息

Wu Tiankun, Meng Xing, Chen Nan, Wang Hongyu, Yang Honghui

机构信息

Department of Pharmacy, The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People's Hospital), Zhengzhou, China.

Emergency Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Heliyon. 2024 Dec 5;10(24):e40988. doi: 10.1016/j.heliyon.2024.e40988. eCollection 2024 Dec 30.

Abstract

We present a highly challenging case of brainstem hemorrhage complicated with pneumonia in a 41-year-old male patient. The patient had intermittent and recurrent fever for nearly two months from June 24, 2022 to August 22, 2022, along with extremely unstable vital signs. Multiple consultations were conducted among clinicians and pharmacists. In view of the patient's actual situation, they initially carried out empirical treatment and then comprehensively considered factors such as the characteristics of anti-infective drugs, interactions, susceptibility testing, and blood drug concentration to analyze and adjust the types and dosages of drugs and implement individualized therapy. Eventually, the patient's body temperature returned to normal, vital signs stabilized, and the patient was discharged smoothly. The author presents this case with the intention of providing a valuable reference for the treatment of patients with cerebral hemorrhage and pneumonia.

摘要

我们呈现了一例极具挑战性的病例,一名41岁男性患者脑干出血并发肺炎。该患者在2022年6月24日至2022年8月22日期间持续近两个月间歇性反复发热,生命体征极不稳定。临床医生和药剂师进行了多次会诊。鉴于患者实际情况,他们先进行了经验性治疗,然后综合考虑抗感染药物特性、相互作用、药敏试验及血药浓度等因素,分析调整药物种类和剂量,实施个体化治疗。最终,患者体温恢复正常,生命体征平稳,顺利出院。作者呈现此病例旨在为脑出血合并肺炎患者的治疗提供有价值的参考。

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