Łokieć Katarzyna, Uchmanowicz Bartosz, Kwaśny Adrian, Kubielas Grzegorz, Smereka Jacek, Surma Stanisław, Dissen Anthony, Czapla Michał
Department of Propaedeutic of Civilization Diseases, Medical University of Lodz, Lodz, Poland.
Institute of Dietetics, The Academy of Business and Health Science, Lodz, Polska.
Vasc Health Risk Manag. 2024 Dec 24;20:579-591. doi: 10.2147/VHRM.S490795. eCollection 2024.
Body mass index (BMI), as a straightforward measure, is widely used in clinical practice, and its results are linked to HT and patient prognosis. This study aimed to ascertain if sex differences exist in the prognostic significance of BMI at the time of admission to the cardiology unit, and how this impacts the LOHS for patients suffering from hypertension.
A retrospective analysis of the medical records of 486 patients admitted urgently with a diagnosis of HT to the Cardiology Department at University Hospital in Wroclaw (Poland) between January 2017 and June 2021 was conducted.
Women accounted for 53% of the study group and were older than men (64.7±12.8 vs 60.5±11.8, p=0.466). The mean BMI in women was 28.49±5.39 and in men 29.14±4.88. In an unadjusted linear regression model BMI results were not independent predictors of LOHS in either sex. After adjusting the model for comorbidities and blood test results, significant independent predictors of LOHS in women were LDL (B=-0.02, p<0.001), HDL (B=-0.043, p=0.012), TC (B=0.015, p=0.007), and hsCRP (B=0.02, p=0.013), while in men they were LDL (B= -0.026, p<0.001), HDL (B= -0.058, p=0.003), and TC (B=0.022, p=0.002).
The result of BMI assessed at the time of a patient's admission to the cardiology department is not a significant predictor of LOHS in both men and women with hypertension.
体重指数(BMI)作为一种简单的测量方法,在临床实践中被广泛应用,其结果与高血压(HT)及患者预后相关。本研究旨在确定在心脏病科住院时BMI的预后意义是否存在性别差异,以及这如何影响高血压患者的住院时间(LOHS)。
对2017年1月至2021年6月期间在波兰弗罗茨瓦夫大学医院心脏病科因高血压诊断而紧急入院的486例患者的病历进行回顾性分析。
女性占研究组的53%,且比男性年龄大(64.7±12.8岁 vs 60.5±11.8岁,p = 0.466)。女性的平均BMI为28.49±5.39,男性为29.14±4.88。在未调整的线性回归模型中,BMI结果在两性中均不是住院时间的独立预测因素。在对合并症和血液检测结果进行模型调整后,女性住院时间的显著独立预测因素为低密度脂蛋白(LDL,B = -0.02,p < 0.001)、高密度脂蛋白(HDL,B = -0.043,p = 0.012)、总胆固醇(TC,B = 0.015,p = 0.007)和超敏C反应蛋白(hsCRP,B = 0.02,p = 0.013),而男性的为低密度脂蛋白(B = -0.026,p < 0.001)、高密度脂蛋白(B = -0.058,p = 0.003)和总胆固醇(B = 0.022,p = 0.002)。
患者入院心脏病科时评估的BMI结果并非高血压男性和女性住院时间的显著预测因素。