Surma Stanisław, Czapla Michał, Uchmanowicz Izabella, Juárez-Vela Raúl, Pietrzykowski Łukasz, Uchmanowicz Bartosz, Leśkiewicz Marcin, Griesmann Krzysztof, Burzyński Michał, Smereka Jacek, Lewandowski Łukasz
Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, 40-752 Katowice, Poland.
Department of Emergency Medical Service, Faculty of Nursing and Midwifery, Wroclaw Medical University, 51-618 Wroclaw, Poland.
Nurs Rep. 2025 Mar 19;15(3):110. doi: 10.3390/nursrep15030110.
: Arterial hypertension (HT) is a leading modifiable risk factor for cardiovascular diseases, often contributing to prolonged lengths of hospital stay (LOHS), which place significant strain on healthcare systems. This study aimed to analyze the factors associated with prolonged lengths of hospital stay in patients with HT, focusing on key biochemical and clinical predictors. : This retrospective study included 356 adult patients hospitalized in the Cardiology Department of the University Hospital in Wroclaw, Poland, between January 2017 and June 2021. Data collected included demographic characteristics, body mass index (BMI), comorbidities, and laboratory parameters. Logistic regression models were used to identify predictors of prolonged LOHS, defined as four or more days, and to evaluate interactions between variables. : Lower levels of low-density lipoprotein cholesterol (LDL-c) and elevated concentrations of high-sensitivity C-reactive protein (hsCRP) were identified as significant predictors of prolonged LOHS, with each 1 mg/dL decrease in LDL-c increasing the odds of prolonged LOHS by 1.21% ( < 0.001) and each 1 mg/L increase in hsCRP raising the odds by 3.80% ( = 0.004). An interaction between sex and heart failure (HF) was also observed. Female patients with HF had 3.995-fold higher odds of prolonged LOHS compared to females without HF ( < 0.001), while no significant difference was found among male patients with or without HF ( = 0.890). : The predictors of prolonged LOHS in patients with HT include lower levels of LDL-c, elevated hsCRP, and the interaction between sex and heart failure (HF). Specifically, female patients with HF demonstrated significantly higher odds of prolonged LOHS compared to females without HF, while this relationship was not observed in male patients.
动脉高血压（HT）是心血管疾病的主要可改变风险因素，常导致住院时间延长（LOHS），给医疗系统带来巨大压力。本研究旨在分析与HT患者住院时间延长相关的因素，重点关注关键的生化和临床预测指标。 这项回顾性研究纳入了2017年1月至2021年6月期间在波兰弗罗茨瓦夫大学医院心内科住院的356例成年患者。收集的数据包括人口统计学特征、体重指数（BMI）、合并症和实验室参数。采用逻辑回归模型确定住院时间延长（定义为4天或更长时间）的预测指标，并评估变量之间的相互作用。 低密度脂蛋白胆固醇（LDL-c）水平降低和高敏C反应蛋白（hsCRP）浓度升高被确定为住院时间延长的重要预测指标，LDL-c每降低1mg/dL，住院时间延长的几率增加1.21%（P<0.001），hsCRP每升高1mg/L，几率增加3.80%（P = 0.004）。还观察到性别与心力衰竭（HF）之间的相互作用。与无HF的女性相比，患有HF的女性患者住院时间延长的几率高3.995倍（P<0.001），而有或无HF的男性患者之间未发现显著差异（P = 0.890）。 HT患者住院时间延长的预测指标包括LDL-c水平降低、hsCRP升高以及性别与心力衰竭（HF）之间的相互作用。具体而言，与无HF的女性相比，患有HF的女性患者住院时间延长的几率显著更高，而男性患者未观察到这种关系。
