老年人口腔脆弱的患病率及影响因素：一项系统评价和荟萃分析
Prevalence and influencing factors of oral frailty in older adults: a systematic review and meta-analysis.
作者信息
Zhou Yutong, Zhou Li, Zhang Wen, Chen Yao, She Keyi, Zhang Hongtao, Gao Yue, Yin Xinhong
机构信息
School of Nursing, University of South China, Hengyang, China.
Department of Hepatobiliary Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China.
出版信息
Front Public Health. 2024 Dec 13;12:1457187. doi: 10.3389/fpubh.2024.1457187. eCollection 2024.
OBJECTIVE
This study aimed to conduct a systematic review and meta-analysis, assessing the pooled prevalence and influencing factors of oral frailty in older people to assist healthcare professionals in enhancing their understanding of this condition and formulating efficient interventions.
METHODS
This systematic review was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-analyses Statement (PRISMA) guidelines. We searched PubMed, Web of Science, The Cochrane Library, Embase, CINAHL, ProQuest, the National Knowledge Infrastructure (CNKI), WAN FANG DATA, VIP Information, SinoMed and Scopus for literature published in English or Chinese from inception to June 19, 2024. Subsequently, we evaluated the potential for bias in the cross-sectional studies that met our criteria through the Agency for Healthcare Research and Quality (AHRQ) tool. In contrast, we utilized the robust Newcastle-Ottawa scale for cohort and case-control studies. We performed statistical analyses using STATA 17 software. Prevalence was studied using a meta-analysis of a single proportion. For influencing factors, dichotomous variables were expressed as odds ratios (ORs) and 95% confidence intervals (Cls), and continuous variables were expressed as weighted mean differences (WMDs) and 95% confidence intervals (Cls).
RESULTS
Investigation into 17 studies encompassing 24,983 participants discovered a striking 28% overall prevalence rate for oral frailty among older individuals (95% CI 20-36%, < 0.001). Upon assessing the literature's quality, nine articles acquired high ratings; all others received medium ratings. These findings imply a complex interplay among biological, socio-economic, lifestyle, and disease-pharmacological factors in the manifestation of oral frailty in older adults.
CONCLUSION
Oral frailty is prevalent in older adults and is impacted by diverse factors. Enhanced surveillance and effective interventions for oral frailty are required in older cohorts.
SYSTEMATIC REVIEW REGISTRATION
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024544552, identifier CRD42024544552.
目的
本研究旨在进行系统评价和荟萃分析，评估老年人口腔脆弱的合并患病率及其影响因素，以帮助医疗保健专业人员加深对该疾病的理解并制定有效的干预措施。
方法
本系统评价依据系统评价和荟萃分析的首选报告项目声明（PRISMA）指南进行。我们检索了PubMed、科学网、考科蓝图书馆、Embase、护理学与健康领域数据库、ProQuest、国家知识基础设施（CNKI）、万方数据、维普资讯、中国生物医学文献数据库和Scopus，以获取从创刊至2024年6月19日发表的英文或中文文献。随后，我们通过医疗保健研究与质量机构（AHRQ）工具评估符合我们标准的横断面研究中的偏倚可能性。相比之下，我们在队列研究和病例对照研究中使用了稳健的纽卡斯尔-渥太华量表。我们使用STATA 17软件进行统计分析。患病率采用单比例荟萃分析进行研究。对于影响因素，二分变量表示为比值比（OR）和95%置信区间（CI），连续变量表示为加权平均差（WMD）和95%置信区间（CI）。
结果
对17项研究（涉及24983名参与者）的调查发现，老年人中口腔脆弱的总体患病率高达28%（95%CI 20 - 36%，P < 0.001）。在评估文献质量时，9篇文章获得高分；所有其他文章获得中等分数。这些发现表明，在老年人口腔脆弱的表现中，生物、社会经济、生活方式和疾病-药理学因素之间存在复杂的相互作用。
结论
口腔脆弱在老年人中普遍存在，并受到多种因素的影响。老年人群需要加强对口腔脆弱的监测和有效的干预措施。
系统评价注册
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024544552，标识符CRD42024544552。
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