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鼻窦平滑肌瘤:一例病例报告及文献综述

Sinonasal Leiomyoma: A Case Report and a Review of the Literature.

作者信息

Adebola Shofoluwe Nurudeen, Halimau Aliyu Oziohu, Yunusa Shuaibu Iliyasu, Abdulrazak Ajiya, Babatunde Mohammed Ibrahim, Damagum Umar Maimuna, Oladigbolu Sanni Rasheedat

机构信息

Division of Ear-Nose and Throat, Department of Surgery, Faculty of Clinical Science, College of Medical Sciences, Ahmadu Bello University and Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

Department of Pathology, Faculty of Basic Clinical Sciences, College of Medical Sciences, Ahmadu Bello University and Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

出版信息

J West Afr Coll Surg. 2025 Jan-Mar;15(1):102-105. doi: 10.4103/jwas.jwas_181_23. Epub 2024 Jul 18.

DOI:10.4103/jwas.jwas_181_23
PMID:39735814
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11676015/
Abstract

Sinonasal leiomyoma is an exceptionally rare neoplasm arising from smooth muscle cells within the sinonasal tract. This abstract presents a case study of a 43-year-old male patient diagnosed with sinonasal leiomyoma, a distinctive and challenging entity in otolaryngology. The patient presented with a complex clinical history, including a 2-year interval between initial evaluation and definitive diagnosis. Initial histology suggested a smooth muscle tumour of uncertain malignant potential, highlighting the diagnostic intricacies associated with this condition. The radiological assessment revealed an extensive soft tissue mass with the involvement of multiple adjacent structures. The patient subsequently underwent surgical resection, leading to a revised histological diagnosis of leiomyoma. This case underscores the diagnostic challenges associated with sinonasal leiomyoma, emphasising the importance of comprehensive evaluation, including clinical history, radiological imaging, and histopathological examination. Long-term follow-up is essential for monitoring potential recurrences and optimising patient outcomes. By presenting this rare case, we aim to contribute to the limited body of literature on sinonasal leiomyoma and highlight the complexities surrounding its diagnosis and management in clinical practice.

摘要

鼻窦平滑肌瘤是一种极其罕见的肿瘤,起源于鼻窦道内的平滑肌细胞。本摘要介绍了一名43岁男性患者的病例研究,该患者被诊断为鼻窦平滑肌瘤,这是耳鼻喉科中一种独特且具有挑战性的病症。患者有复杂的临床病史,包括初次评估与最终确诊之间间隔了2年。初始组织学检查提示为恶性潜能不确定的平滑肌瘤,凸显了与该病症相关的诊断复杂性。影像学评估显示有一个广泛的软组织肿块,累及多个相邻结构。患者随后接受了手术切除,最终组织学诊断修订为平滑肌瘤。该病例强调了鼻窦平滑肌瘤相关的诊断挑战,突出了综合评估的重要性,包括临床病史、影像学检查和组织病理学检查。长期随访对于监测潜在复发和优化患者预后至关重要。通过呈现这一罕见病例,我们旨在为关于鼻窦平滑肌瘤的有限文献做出贡献,并强调临床实践中其诊断和管理的复杂性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/2457cc36e51e/JWACS-15-102-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/7ced9ae90bd3/JWACS-15-102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/a074341e2bec/JWACS-15-102-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/5ec9d935afc0/JWACS-15-102-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/b8fdf8e44c23/JWACS-15-102-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/2457cc36e51e/JWACS-15-102-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/7ced9ae90bd3/JWACS-15-102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/a074341e2bec/JWACS-15-102-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/5ec9d935afc0/JWACS-15-102-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/b8fdf8e44c23/JWACS-15-102-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d78/11676015/2457cc36e51e/JWACS-15-102-g005.jpg

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本文引用的文献

1
Smooth muscle tumour of uncertain malignant potential (SMTUMP) in the nasal cavity: an incidental finding.鼻腔中具有不确定恶性潜能的平滑肌瘤(SMTUMP):一项偶然发现。
BMJ Case Rep. 2016 Nov 22;2016:bcr2016217386. doi: 10.1136/bcr-2016-217386.
2
Leiomyoma of the sinonasal cavity: CT and MRI findings.鼻腔鼻窦平滑肌瘤:CT 和 MRI 表现。
Clin Radiol. 2009 Dec;64(12):1203-9. doi: 10.1016/j.crad.2009.05.014. Epub 2009 Oct 9.
3
Cellular leiomyoma of the nasal cavity: findings of CT and MR imaging.鼻腔细胞性平滑肌瘤:CT与MR成像表现
AJNR Am J Neuroradiol. 2005 Jun-Jul;26(6):1336-8.
4
Sinonasal leiomyoma: report of 2 cases.鼻窦平滑肌瘤:2例报告。
Ear Nose Throat J. 2005 Apr;84(4):224, 226-30.
5
Sinonasal smooth muscle cell tumors: a clinicopathologic and immunohistochemical analysis of 12 cases with emphasis on the low-grade end of the spectrum.鼻窦平滑肌细胞瘤:12例临床病理及免疫组化分析,重点关注谱系低端的低级别病变
Arch Pathol Lab Med. 2003 Mar;127(3):297-304. doi: 10.5858/2003-127-0297-SSMCT.
6
Leiomyoma of the nasal septum.鼻中隔平滑肌瘤
Rhinology. 2001 Dec;39(4):233-5.
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Leiomyoma of the inferior turbinates.下鼻甲平滑肌瘤
J Otolaryngol. 2000 Feb;29(1):55-6.
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Vascular leiomyoma with abundant adipose cells of the nasal cavity.鼻腔富于脂肪细胞的血管平滑肌瘤。
Am J Otolaryngol. 1998 Jan-Feb;19(1):50-3. doi: 10.1016/s0196-0709(98)90066-7.
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Sinonasal leiomyomas.鼻窦平滑肌瘤。
Otolaryngol Head Neck Surg. 1994 Nov;111(5):660-4. doi: 10.1177/019459989411100520.
10
Leiomyoma of the nasal cavity.鼻腔平滑肌瘤
J Laryngol Otol. 1988 Sep;102(9):831-3. doi: 10.1017/s0022215100106590.