Borda Miguel Germán, Landi Francesco, Cederholm Tommy, Venegas-Sanabria Luis Carlos, Duque Gustavo, Wakabayashi Hidetaka, Barreto George E, Rodriguez-Sanchez Isabel, Canevelli Marco, Cano-Gutierrez Carlos, Pérez-Zepeda Mario Ulises, Wallace Lindsay, Rockwood Kenneth, Salas-Carrillo Mario, Gjestsen Martha, Testad Ingelin, Ballard Clive, Aarsland Dag
Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Stavanger, Norway; Department of Neurology, Clínica Universidad de Navarra, Pamplona, Spain; Centro de Investigación en Ciencias de la Salud, Facultad de Ciencias de la Salud, Universidad Anáhuac México, Huixquilucan Edo de México, México; Semillero de Neurociencias y Envejecimiento, Ageing Institute, Medical School, Pontificia Universidad Javeriana, Bogotá, Colombia.
Department of Geriatrics and Orthopedics, Fondazione Policlinico Universitario "A. Gemelli", Istituto di Ricovero e Cura a Carattere Scientifico, Università Cattolica del Sacro Cuore, Rome, Italy.
Lancet Healthy Longev. 2025 Jan;6(1):100666. doi: 10.1016/j.lanhl.2024.100666. Epub 2024 Dec 27.
Frailty complicates the care of individuals with dementia, increasing their vulnerability to adverse outcomes. This Personal View presents expert recommendations for managing frailty in individuals with dementia, aimed at health-care providers, particularly those in primary care. We conducted a rapid literature review followed by a consensus process involving 18 international experts on dementia and frailty. The experts identified key areas, including diagnosis of frailty, assessment of nutritional status and nutritional management, physical activity, prevention of falls, and polypharmacy management. The recommendations emphasise early identification of frailty and a comprehensive, interdisciplinary approach to care that aims to maintain the individual's daily functioning, quality of life, and independence. The recommendations highlight the importance of tailored interventions, regular monitoring, and the integration of psychosocial support into the therapeutic approach. These recommendations address a crucial gap in existing clinical guidelines, offering practical guidance for clinicians managing frailty in individuals with dementia.
衰弱使痴呆症患者的护理变得复杂，增加了他们出现不良后果的易感性。这篇个人观点文章为痴呆症患者的衰弱管理提供了专家建议，目标受众是医疗保健提供者，尤其是初级保健领域的人员。我们进行了快速文献综述，随后开展了一个由18位痴呆症和衰弱领域的国际专家参与的共识达成过程。专家们确定了关键领域，包括衰弱的诊断、营养状况评估和营养管理、身体活动、跌倒预防以及多重用药管理。这些建议强调早期识别衰弱以及采用全面、跨学科的护理方法，旨在维持个体的日常功能、生活质量和独立性。建议突出了量身定制干预措施、定期监测以及将心理社会支持融入治疗方法的重要性。这些建议弥补了现有临床指南中的一个关键空白，为临床医生管理痴呆症患者的衰弱提供了实用指导。
