Araki Kentaro, Hirano Yoshiyuki, Kurita Kohei, Shimizu Eiji
Research Center for Child Mental Development, Chiba University, Chiba 260-8670, Japan.
J Stroke Cerebrovasc Dis. 2025 Feb;34(2):108217. doi: 10.1016/j.jstrokecerebrovasdis.2024.108217. Epub 2024 Dec 28.
Non-verbal Screening Test for Aphasia and Dysarthria scores correlate with post-stroke cognitive function; however, their correlations with activities of daily living dependency and home discharge (cognitive function-associated outcomes) remain unclear. We investigated the correlation of these scores with activities of daily living dependency and home discharge outcomes.
Disability levels and functional outcomes of 278 inpatients with brain injury (age: 72.8 ± 13.0 years) were evaluated using the modified Rankin Scale. Patients were grouped according to activities of daily living dependency (independent [n = 96; modified Rankin Scale score≤2]) and non-home discharge (n = 126) status. Factors predicting home discharge were analyzed using univariate and multivariate logistic regression analyses.
Cognitive impairment was more prevalent in the activities of daily living-dependent group than in the independent group (odds ratio: 6.34 [95 % confidence interval: 3.57-11.52]; p < 0.001) and in the non-home discharge than in the home discharge group (2.78 [1.65-4.73]; p < 0.001). Non-verbal test scores correlated moderately with activities of daily living independence and home discharge. Age, modified Rankin Scale score, cognitive impairment, and the Screening Test for Aphasia and Dysarthria scores were significantly associated with home discharge in univariate analyses. Only modified Rankin Scale and non-verbal test scores were significantly associated with home discharge in multivariate analysis (p < 0.001).
Non-verbal test scores were significantly associated with activities of daily living independence and home discharge in patients with stroke. The non-verbal test, being less influenced by communicative disorders, offers a novel tool for estimating cognitive function.
失语症和构音障碍的非言语筛查测试得分与中风后的认知功能相关；然而，它们与日常生活依赖性和出院回家（认知功能相关结果）之间的相关性仍不明确。我们研究了这些得分与日常生活依赖性和出院回家结果之间的相关性。
使用改良Rankin量表评估278例脑损伤住院患者（年龄：72.8±13.0岁）的残疾水平和功能结局。根据日常生活依赖性（独立[n = 96；改良Rankin量表得分≤2]）和未出院回家（n = 126）状态对患者进行分组。使用单因素和多因素逻辑回归分析来分析预测出院回家的因素。
认知障碍在日常生活依赖组中比独立组更普遍（优势比：6.34 [95%置信区间：3.57 - 11.52]；p < 0.001），在未出院回家组中比出院回家组更普遍（2.78 [1.65 - 4.73]；p < 0.001）。非言语测试得分与日常生活独立性和出院回家呈中度相关。在单因素分析中，年龄、改良Rankin量表得分、认知障碍以及失语症和构音障碍筛查测试得分与出院回家显著相关。在多因素分析中，只有改良Rankin量表和非言语测试得分与出院回家显著相关（p < 0.001）。
非言语测试得分与中风患者的日常生活独立性和出院回家显著相关。非言语测试受沟通障碍的影响较小，为评估认知功能提供了一种新工具。
