Khadka Khim Bahadur, Koirala Nabina, Ivanova Olena, Bastola Ramchandra, Singh Dela, Magar Kamala Rana, Banstola Bidhya, Adhikari Ramesh Prasad, Giedraitis Vincentas, Paudel Deepak, Froeschl Guenter
Health Directorate, Ministry of Social Development and Health, Pokhara, Gandaki Province, Nepal.
Center for International Health, LMU, Munich, Germany.
BMC Pregnancy Childbirth. 2024 Dec 31;24(1):883. doi: 10.1186/s12884-024-07120-8.
Despite recent improvements in the overall health status of Nepal's population, newborn morbidities and mortalities have remained a challenge. This study explores the situation and care strategies for newborn health problems in the Gandaki Province of Nepal.
This is a retrospective hospital records analysis. A structured questionnaire was employed to collect data on socio-demographic, clinical, and outcome variables in 1,355 newborns admitted to the Special Newborn Care Unit (SNCU) between May 1, 2021, and April 30, 2022, in five hospitals within the Gandaki Province.
Among all newborns, 60% were male, and 40% belonged to Janajati indigenous families. The mean age of mothers at the time of delivery was 24.4 years; the average birth weight of babies was 2.8 kg; and the gestational week was 38 weeks. Around 96% of births occurred in healthcare facilities. The average inpatient hospital stay was 4.7 days. The reasons for SNCU admission were newborn sepsis (51%), neonatal hyperbilirubinemia (23%), respiratory distress syndrome (18%), and low birth weight (11%). Approximately 7% of the newborns were found to have died due to various causes, including sepsis, asphyxia, and indirect medical reasons. Female newborns had a 0.45-times (CI: 0.23-0.84) lower risk of mortality compared to male newborns. Underweight newborns had 8.8 times (CI: 4.5-17.2) higher risk of death than newborns with a normal birth weight, even after adjusting for other factors like sex, delivery site, mode of delivery, mother's age, respiratory distress syndrome, neonatal hyperbilirubinemia, neonatal sepsis, and age at admission to SNCU. The most common treatments included injectable antibiotics (73%), intravenous fluids (53%), oxygen delivery (39%), and phototherapy (36%), while 3% received "Kangaroo Mother Care (KMC)".
The study showed that newborns suffered from multiple health complications such as sepsis, hyperbilirubinemia, or asphyxia, and many newborns received essential medical services from hospitals. Birth weight, sex of the newborn, and respiratory distress syndrome were significantly associated with neonatal mortality. Hospitals should focus on reinforcing KMC, neonatal resuscitation, and early infection control measures.
尽管尼泊尔人口的整体健康状况最近有所改善,但新生儿发病率和死亡率仍然是一项挑战。本研究探讨了尼泊尔甘达基省新生儿健康问题的情况及护理策略。
这是一项回顾性医院记录分析。采用结构化问卷收集2021年5月1日至2022年4月30日期间在甘达基省五家医院的特殊新生儿护理病房(SNCU)收治的1355例新生儿的社会人口统计学、临床和结局变量数据。
在所有新生儿中,60%为男性,40%属于贾纳贾蒂土著家庭。分娩时母亲的平均年龄为24.4岁;婴儿的平均出生体重为2.8千克;孕周为38周。约96%的分娩在医疗机构进行。平均住院天数为4.7天。入住SNCU的原因包括新生儿败血症(51%)、新生儿高胆红素血症(23%)、呼吸窘迫综合征(18%)和低出生体重(11%)。约7%的新生儿因各种原因死亡,包括败血症、窒息和间接医疗原因。与男婴相比,女婴的死亡风险低0.45倍(CI:0.23 - 0.84)。即使在调整了性别、分娩地点、分娩方式、母亲年龄、呼吸窘迫综合征、新生儿高胆红素血症、新生儿败血症和入住SNCU时的年龄等其他因素后,低体重新生儿的死亡风险仍比正常出生体重的新生儿高8.8倍(CI:4.5 - 17.2)。最常见的治疗方法包括注射用抗生素(73%)、静脉输液(53%)、输氧(39%)和光疗(36%),而3%接受了“袋鼠式护理(KMC)”。
研究表明,新生儿患有败血症、高胆红素血症或窒息等多种健康并发症,许多新生儿从医院获得了基本医疗服务。出生体重、新生儿性别和呼吸窘迫综合征与新生儿死亡率显著相关。医院应注重加强袋鼠式护理、新生儿复苏和早期感染控制措施。