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降低尼泊尔偏远地区的新生儿死亡率:关于挑战、差异及“帮助婴儿呼吸”(HBB)项目作用的叙述性综述

Reducing Neonatal Mortality in Nepal's Remote Regions: A Narrative Review of Challenges, Disparities, and the Role of Helping Babies Breathe (HBB).

作者信息

Kain Victoria Jane, Dhungana Ranjan, Dhungana Animesh

机构信息

School of Nursing and Midwifery, Brisbane South Campus, Griffith University, 170 Kessels Road, Brisbane, QLD 4111, Australia.

Safa Sunaulo Nepal, Kathmandu 44600, Nepal.

出版信息

Pediatr Rep. 2025 Apr 17;17(2):48. doi: 10.3390/pediatric17020048.

DOI:10.3390/pediatric17020048
PMID:40278528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12030588/
Abstract

BACKGROUND

Nepal's diverse geography creates significant challenges for healthcare accessibility, particularly for neonatal care. Rural areas, especially in the mountainous regions, face severe healthcare gaps due to isolation, inadequate infrastructure, and a shortage of skilled staff. Strengthening healthcare in these underserved regions is essential to reducing neonatal mortality. Helping Babies Breathe (HBB) is a neonatal resuscitation training program designed to reduce neonatal mortality due to birth asphyxia in low-resource settings.

METHODS

A comprehensive literature search identified studies on neonatal mortality and interventions, particularly HBB, which were analyzed using a narrative synthesis approach. This review examines disparities in neonatal health outcomes, regional differences, and barriers to healthcare access.

FINDINGS

This review identifies key themes related to healthcare disparities, neonatal mortality, and birth outcomes in Nepal's remote regions. Geographical isolation, inadequate healthcare infrastructure, and cultural barriers contribute to persistently high neonatal mortality, particularly in mountainous areas such as Jumla and Dolpa, where rates exceed 60 per 1000 live births. HBB has shown a significant impact, reducing neonatal mortality by up to 60% when effectively implemented. However, infrastructural gaps, lack of emergency transport, and the uneven distribution of skilled birth attendants (SBAs) remain critical challenges. Addressing these disparities requires expanded training, increased availability of neonatal resuscitation equipment, and culturally sensitive healthcare strategies.

摘要

背景

尼泊尔多样的地理环境给医疗服务的可及性带来了重大挑战,尤其是新生儿护理方面。农村地区,特别是山区,由于地处偏远、基础设施不足以及缺乏技术人员,面临着严重的医疗服务差距。加强这些服务不足地区的医疗保健对于降低新生儿死亡率至关重要。“帮助婴儿呼吸”(HBB)是一项新生儿复苏培训计划,旨在降低资源匮乏地区因出生窒息导致的新生儿死亡率。

方法

通过全面的文献检索,确定了关于新生儿死亡率和干预措施的研究,特别是HBB,采用叙述性综合方法进行分析。本综述考察了新生儿健康结果的差异、地区差异以及医疗服务可及性的障碍。

结果

本综述确定了与尼泊尔偏远地区医疗保健差距、新生儿死亡率和出生结局相关的关键主题。地理隔离、医疗基础设施不足和文化障碍导致新生儿死亡率持续居高不下,特别是在朱木拉和多尔帕等山区,每1000例活产的死亡率超过60例。HBB已显示出显著影响,有效实施时可将新生儿死亡率降低多达60%。然而,基础设施差距、缺乏紧急运输以及熟练助产士(SBA)分布不均仍然是关键挑战。解决这些差距需要扩大培训、增加新生儿复苏设备的供应以及采用对文化敏感的医疗保健策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/12030588/a07d5817067f/pediatrrep-17-00048-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/12030588/a07d5817067f/pediatrrep-17-00048-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/12030588/a07d5817067f/pediatrrep-17-00048-g001.jpg

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本文引用的文献

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Newborn morbidities and care procedures at the special newborn care units of Gandaki Province, Nepal: a retrospective study.尼泊尔甘达基省特殊新生儿护理单位的新生儿发病率及护理程序:一项回顾性研究
BMC Pregnancy Childbirth. 2024 Dec 31;24(1):883. doi: 10.1186/s12884-024-07120-8.
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Three Climate and Health Lessons from Nepal Ahead of COP28.在COP28之前,从尼泊尔汲取的三条气候与健康经验教训。
NAM Perspect. 2023 Nov 29;2023. doi: 10.31478/202311f. eCollection 2023.
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Changes in health facility readiness for obstetric and neonatal care services in Nepal: an analysis of cross-sectional health facility survey data in 2015 and 2021.
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BMC Pregnancy Childbirth. 2024 Jan 24;24(1):79. doi: 10.1186/s12884-023-06138-8.
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"Knowledge regarding cardiopulmonary resuscitation among health assistants in Nepal: A cross-sectional study".尼泊尔卫生助理人员心肺复苏知识:一项横断面研究。
PLoS One. 2023 Nov 9;18(11):e0293323. doi: 10.1371/journal.pone.0293323. eCollection 2023.
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Overcoming the challenges facing Nepal's health system during federalisation: an analysis of health system building blocks.克服联邦化时期尼泊尔卫生系统面临的挑战:对卫生系统组成部分的分析。
Health Res Policy Syst. 2023 Nov 2;21(1):117. doi: 10.1186/s12961-023-01033-2.
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Service availability and readiness for basic emergency obstetric and newborn care: Analysis from Nepal Health Facility Survey 2021.基本产科和新生儿急救服务的提供情况和准备情况:来自尼泊尔卫生机构调查 2021 年的分析。
PLoS One. 2023 Aug 17;18(8):e0282410. doi: 10.1371/journal.pone.0282410. eCollection 2023.
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A critical analysis of health system in Nepal; Perspective's based on COVID-19 response.尼泊尔卫生系统的批判性分析;基于对新冠疫情应对措施的视角
Dialogues Health. 2023 Dec;3:100142. doi: 10.1016/j.dialog.2023.100142. Epub 2023 Jun 10.
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Modified Pathway to Survival highlights importance of rapid access to quality institutional delivery care to decrease neonatal mortality in Serang and Jember districts, Java, Indonesia.改良生存路径强调了在印度尼西亚爪哇省的塞尔朗和詹贝地区,快速获得高质量机构分娩护理的重要性,以降低新生儿死亡率。
J Glob Health. 2023 Apr 14;13:04020. doi: 10.7189/jogh.13.04020.
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Association of geographic distribution and birth weight with sociodemographic factors of the maternal and newborn child of hilly and mountain regions of eastern Nepal: a cross-sectional study.尼泊尔东部丘陵和山区母婴的地理分布和出生体重与社会人口因素的关联:一项横断面研究。
BMJ Paediatr Open. 2022 Nov;6(1). doi: 10.1136/bmjpo-2022-001579.
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