Ramos Marta, Seguro Paula Filipe, Carvalho Alexandre, Pinheiro Marta, Ramos Armindo
Intensive Care Unit, Hospital de Cascais, Lisboa, PRT.
Immune Response and Vascular Disease, NOVA Medical School, NOVA University of Lisbon, iNOVA4Health, Lisboa, PRT.
Cureus. 2024 Nov 30;16(11):e74824. doi: 10.7759/cureus.74824. eCollection 2024 Nov.
Kawasaki disease (KD) is an inflammatory condition more common in children but rare in adults, where diagnosis can be challenging due to nonspecific symptoms. Early recognition is essential to prevent severe complications. We present the case of a 26-year-old male with adult-onset KD who initially presented with vague symptoms, resulting in diagnostic delays. The condition progressed to life-threatening cardiovascular complications, including coronary artery aneurysms, underscoring the critical need for prompt identification and management. Timely treatment with intravenous immunoglobulin and corticosteroids led to clinical improvement and prevention of further cardiac damage. This case highlights the importance of heightened clinical awareness of KD in adults and the necessity of a proactive diagnostic approach. Future research should aim to refine diagnostic criteria for adult KD and explore strategies for improving early detection and long-term cardiovascular outcomes in this rare population.
川崎病(KD)是一种炎症性疾病,在儿童中更为常见,在成人中则较为罕见,由于症状不具特异性,其诊断可能具有挑战性。早期识别对于预防严重并发症至关重要。我们报告一例26岁成年男性患成人型川崎病的病例,该患者最初表现为模糊症状,导致诊断延迟。病情进展为危及生命的心血管并发症,包括冠状动脉瘤,这突出了及时识别和管理的迫切需求。静脉注射免疫球蛋白和皮质类固醇的及时治疗使临床症状得到改善,并预防了进一步的心脏损伤。该病例强调了提高对成人川崎病临床认识的重要性以及积极诊断方法的必要性。未来的研究应致力于完善成人川崎病的诊断标准,并探索改善这一罕见人群早期检测和长期心血管结局的策略。