链激酶溶解右心房血栓。

Streptokinase dissolution of a right atrial thrombus.

作者信息

Olsen M M, Blumer J L, Gauderer M W, Izant R J

出版信息

J Pediatr Surg. 1985 Feb;20(1):19-21. doi: 10.1016/s0022-3468(85)80384-5.

Abstract

A critically ill 20-month-old white male with severe bronchopulmonary dysplasia, cor pulmonale, and intolerance to enteral feeds, required a left percutaneous subclavian Broviac catheter. Echocardiogram showed a right atrial thrombus, resolution of which was demonstrated after infusion of streptokinase through the Broviac catheter for 16 hours. The catheter remained in place, functioning well, for a further 4 months. The patient suffered no bleeding complications, and was spared the prohibitive risk of right atrial thrombectomy. This use of streptokinase has not previously been reported.

摘要

一名患有严重支气管肺发育不良、肺心病且不耐受肠内喂养的20个月大危重新生白人男性，需要一根经皮左锁骨下静脉置入的Broviac导管。超声心动图显示右心房有血栓，通过Broviac导管输注链激酶16小时后血栓溶解。导管继续留置4个月，功能良好。患者未出现出血并发症，避免了右心房血栓切除术带来的高风险。此前尚未有关于链激酶这种用法的报道。