Alves Jorge Sara, Van den Broucke Stephan, Koumba Maguena Ruth-Janet, Spinewine Anne
Institut of Health and Society, Université Catholique de Louvain, Woluwé, Belgium.
Psychological Science Research Institute, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
Public Health Nurs. 2025 Mar-Apr;42(2):1084-1114. doi: 10.1111/phn.13516. Epub 2024 Dec 30.
Deprescribing is a strategy to optimize medication use and to prevent medication harm. Despite the fact that behavioral theories have been shown to be useful in explaining health behaviors, the literature on deprescribing relies almost exclusively on attitudes as an explanatory factor for deprescribing behavior. This study systematically reviews the literature that made explicit use of the constructs included in health behavior theories (HBTs) to explain older adults' and informal caregivers' deprescribing behavior and outcomes.
Studies were screened from five electronic databases by two reviewers. Quantitative interventional and non-interventional studies applying at least one HBTs or construct from these theories to older adults' or informal caregiver' intention or behavior to deprescribe, were included. Studies that used the patients' attitudes toward deprescribing (PATD) questionnaire or its revised version were excluded.
A total of 11 non-interventional studies and 11 interventional studies were identified, seven of which applied HBTs, and the other 15 used constructs from the HBTs. Health literacy and locus of control were identified as moderator variables. Only two studies targeted informal caregivers' deprescribing intentions or behavior.
HBTs are not systematically used. However, combining the main HBT constructs reported in the literature offers a better explanation of the (intention to) engage in deprescribing.
The study protocol (ID: CRD42022378157) was published on PROSPERO.
减药是一种优化药物使用并预防药物伤害的策略。尽管行为理论已被证明有助于解释健康行为，但关于减药的文献几乎完全依赖态度作为减药行为的解释因素。本研究系统回顾了明确使用健康行为理论（HBTs）中的概念来解释老年人及非正式照护者减药行为和结果的文献。
两名评审员从五个电子数据库中筛选研究。纳入至少应用一种HBTs或这些理论中的概念来研究老年人或非正式照护者减药意图或行为的定量干预性和非干预性研究。排除使用患者减药态度问卷（PATD）或其修订版的研究。
共识别出11项非干预性研究和11项干预性研究，其中7项应用了HBTs，另外15项使用了HBTs中的概念。健康素养和控制点被确定为调节变量。仅有两项研究针对非正式照护者的减药意图或行为。
HBTs未被系统使用。然而，结合文献中报道的主要HBT概念能更好地解释参与减药的（意图）。
研究方案（ID：CRD42022378157）已在PROSPERO上发表。
