Sabbagh Lana, Abubakir Malaka, Debajawish Sana, Khalil Ghaiyath, Hamdan Mohammed, Al-Kanj Hussein
University of Aleppo, Faculty of Medicine, Aleppo, Syria.
University of Aleppo, Faculty of Medicine, Aleppo, Syria.
Int J Surg Case Rep. 2025 Jan;126:110760. doi: 10.1016/j.ijscr.2024.110760. Epub 2024 Dec 27.
Leriche syndrome (LS), or aortoiliac occlusive disease, is a rare form of peripheral arterial disease leading to claudication, impotence, and diminished femoral pulses due to atheromatous obstruction of the infrarenal aorta and common iliac arteries. Early identification is crucial as untreated LS can result in severe complications. Treatment primarily involves surgical interventions, with endovascular options considered as alternatives.
A 30-year-old former smoker woman presented with calf pain after walking less than 50 m, coupled with a history of recurrent lower extremity arterial occlusions and previous abdominal aorta stenting. Examination revealed pallor and non-palpable pulses in both feet. Doppler imaging and CT scans indicated significant aortic stenosis and iliac artery occlusion. Following a successful bilateral aorto-femoral bypass, distal pulses improved, and the ankle-brachial index was 1 in both limbs. The patient was prescribed warfarin for ongoing management, emphasizing the importance of timely intervention in LS to restore limb perfusion.
LS is characterized by atheromatous obstruction of the infrarenal aorta and iliac arteries, causing claudication and absent femoral pulses. Diagnostic tools include the ankle-brachial index, Doppler ultrasound, and CT angiography. Management typically involves aortofemoral bypass or endovascular revascularization, coupled with lifestyle modifications.
Leriche syndrome poses significant morbidity if undiagnosed. This case highlights its impact on quality of life and limb ischemia risk, underscoring the need for accurate diagnostics and timely, personalized management for improved outcomes. Increased clinician awareness is vital for optimal care.
勒里什综合征(LS),即主髂动脉闭塞性疾病,是一种罕见的外周动脉疾病,由于肾下腹主动脉和髂总动脉的动脉粥样硬化阻塞,导致跛行、阳痿和股动脉搏动减弱。早期识别至关重要,因为未经治疗的LS可导致严重并发症。治疗主要包括手术干预,血管内治疗可作为替代方案。
一名30岁的 former smoker 女性,行走不到50米后出现小腿疼痛,并有复发性下肢动脉闭塞病史和既往腹主动脉支架置入史。检查发现双足苍白且触不到脉搏。多普勒成像和CT扫描显示严重的主动脉狭窄和髂动脉闭塞。成功进行双侧主动脉-股动脉搭桥术后,远端脉搏改善,双下肢踝肱指数均为1。患者被处方华法林进行持续治疗,强调了对LS及时干预以恢复肢体灌注的重要性。
LS的特征是肾下腹主动脉和髂动脉的动脉粥样硬化阻塞,导致跛行和股动脉搏动消失。诊断工具包括踝肱指数、多普勒超声和CT血管造影。治疗通常包括主动脉-股动脉搭桥或血管内血运重建,同时进行生活方式调整。
如果未被诊断,勒里什综合征会导致严重的发病率。本病例突出了其对生活质量和肢体缺血风险的影响,强调了准确诊断和及时、个性化治疗以改善预后的必要性。提高临床医生的认识对优化治疗至关重要。