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2020年阿尔巴尼亚烧伤创面感染的流行病学趋势

Epidemiological trends for burn wound infections in 2020 in albania.

作者信息

Deda L, Belba M K

机构信息

Department of Biomedical and Experimental Courses, Faculty of Medicine, University of Medicine, Tirana, Albania.

Department of Surgery, Service of Burns and Plastic Surgery, Service of Anesthesiology, University Hospital Center "Mother Teresa", Tirana, Albania.

出版信息

Ann Burns Fire Disasters. 2024 Dec 31;37(4):270-280. eCollection 2024 Dec.

Abstract

The burn patient is at high hazard for nosocomial infections (NI) as a result of the nature of the burn damage itself, the immune-compromising impacts of burns, prolonged clinic stays, and intensive diagnostic and therapeutic strategies. The aim of this study is to describe the actual epidemiology of burn wound colonization and infection in the Intensive Care Unit (ICU) of the Service of Burns and Plastic Surgery at the University Hospital Center in Tirana, Albania. The study is retrospective clinical and analytical. Microbiology data, total body surface area (TBSA), patient days (LOS) and mortality were collected from a hospital database for all patients admitted to the ICU of the Service of Burns at the UHC in Tirana, Albania in 2020. The burn wound infection prevalence rate was greater than in 2010 (17.2 vs. 12 infections per 100 patients), while the burn wound colonization prevalence rate was reduced by half (20.6 vs. 44 colonized patients for 100 patients). The burn wound infection incidence rate was increased (47 vs. 42.6 infections per 1000 hospitalization days) and also the attack rate was increased (0.7 vs. 0.5 infections for 100 patients in 2010). The main pathogens were gram-positive bacteria (60 strains; 71%), followed by Gram-negative bacteria (22 strains; 26%), and fungi (3 strains; 3%). The predominant five bacteria were (55.0%), (9%), (8%), (8%) and (5%). (MRSA) accounted for 55.3% (31/56) of Staphylococcal isolates. Implementation of anti-microbial stewardship programs is necessary to optimize the treatment of sepsis.

摘要

由于烧伤损伤本身的性质、烧伤对免疫功能的损害、长期住院、以及强化诊断和治疗策略,烧伤患者发生医院感染(NI)的风险很高。本研究的目的是描述阿尔巴尼亚地拉那大学医院中心烧伤与整形外科重症监护病房(ICU)烧伤创面定植和感染的实际流行病学情况。该研究为回顾性临床分析研究。从阿尔巴尼亚地拉那大学医院中心烧伤科ICU 2020年收治的所有患者的医院数据库中收集微生物学数据、总体表面积(TBSA)、住院天数(LOS)和死亡率。烧伤创面感染患病率高于2010年(每100例患者中感染例数分别为17.2例和12例),而烧伤创面定植患病率减半(每100例患者中定植例数分别为20.6例和44例)。烧伤创面感染发病率有所上升(每1000个住院日感染例数分别为47例和42.6例),2010年每100例患者的感染发病率也有所上升(分别为0.7例和0.5例)。主要病原体为革兰氏阳性菌(60株;71%),其次是革兰氏阴性菌(22株;26%)和真菌(3株;3%)。占主导地位的五种细菌分别是(55.0%)、(9%)、(8%)、(8%)和(5%)。耐甲氧西林金黄色葡萄球菌(MRSA)占葡萄球菌分离株的55.3%(31/56)。实施抗菌管理计划对于优化脓毒症治疗很有必要。

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Epidemiology of infections in a burn unit, Albania.阿尔巴尼亚烧伤病房感染的流行病学。
Burns. 2013 Nov;39(7):1456-67. doi: 10.1016/j.burns.2013.03.013. Epub 2013 Apr 28.

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