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The Effects of Appropriate Perioperative Exercise on Perioperative Neurocognitive Disorders: a Narrative Review.适当的围手术期运动对围手术期神经认知障碍的影响:叙事性综述。
Mol Neurobiol. 2024 Jul;61(7):4663-4676. doi: 10.1007/s12035-023-03864-0. Epub 2023 Dec 19.
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Postoperative Cognitive Impairment and Pain Perception after Abdominal Surgery-Could Immersive Virtual Reality Bring More? A Clinical Approach.术后认知障碍与腹部手术后疼痛感知——沉浸式虚拟现实技术能否带来更多改善?一种临床方法。
Medicina (Kaunas). 2023 Nov 17;59(11):2034. doi: 10.3390/medicina59112034.
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High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) on global cognitive function of elderly in mild to moderate Alzheimer's disease: a systematic review and meta-analysis.高频重复经颅磁刺激(HF-rTMS)对轻中度阿尔茨海默病老年患者整体认知功能的影响:系统评价和荟萃分析。
Neurol Sci. 2024 Jan;45(1):13-25. doi: 10.1007/s10072-023-07072-5. Epub 2023 Sep 26.
4
Resolution of elevated interleukin-6 after surgery is associated with return of normal cognitive function.手术后白细胞介素-6 水平的降低与认知功能的恢复正常有关。
Br J Anaesth. 2023 Oct;131(4):694-704. doi: 10.1016/j.bja.2023.05.023. Epub 2023 Jun 27.
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Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction.运动改善认知功能障碍的分子机制研究进展。
Transl Neurodegener. 2023 Feb 27;12(1):9. doi: 10.1186/s40035-023-00341-5.
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Efficacy of transcranial direct current stimulation on postoperative delirium in elderly patients undergoing lower limb major arthroplasty: A randomized controlled trial.经颅直流电刺激对老年下肢大关节置换术后谵妄的疗效:一项随机对照试验。
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Emotion recognition dysfunction after anesthesia and cardiac surgery.麻醉和心脏手术后的情绪识别功能障碍。
Front Psychol. 2022 Nov 16;13:1001493. doi: 10.3389/fpsyg.2022.1001493. eCollection 2022.
8
Effects of repetitive transcranial magnetic stimulation on post-stroke patients with cognitive impairment: A systematic review and meta-analysis.重复经颅磁刺激治疗脑卒中后认知障碍患者的效果:系统评价和 Meta 分析。
Behav Brain Res. 2023 Feb 15;439:114229. doi: 10.1016/j.bbr.2022.114229. Epub 2022 Nov 25.
9
Improving quality of life post-tumor craniotomy using personalized, parcel-guided TMS: safety and proof of concept.采用个体化、区向导经颅磁刺激改善肿瘤手术后患者的生活质量:安全性和概念验证。
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10
Dose-dependent relationship between intra-procedural hypoxaemia or hypocapnia and postoperative delirium in older patients.老年患者术中低氧血症或低碳酸血症与术后谵妄之间的剂量依赖关系。
Br J Anaesth. 2023 Feb;130(2):e298-e306. doi: 10.1016/j.bja.2022.08.032. Epub 2022 Oct 1.

老年心脏手术后患者的术后认知功能障碍:康复应用研究进展

Postoperative cognitive dysfunction in elderly postcardiac surgery patients: progress in rehabilitation application research.

作者信息

Zhang Zhen-Rong, Li Yang-Zheng, Wu Xiao-Qing, Chen Wen-Jun, Xu Jian, Zhao Wei-Hua, Gong Xiao-Yan

机构信息

Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Department of Rehabilitation Medicine, The First People's Hospital of Shizuishan, Shizuishan, Ningxia, China.

出版信息

Front Rehabil Sci. 2024 Dec 17;5:1525813. doi: 10.3389/fresc.2024.1525813. eCollection 2024.

DOI:10.3389/fresc.2024.1525813
PMID:39741908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11686598/
Abstract

Postoperative cognitive dysfunction (POCD) is a prevalent complication of the central nervous system in elderly patients following cardiac surgery. This review aims to provide an overview of the etiology, risk factors, diagnostic assessment, and rehabilitation strategies for cognitive dysfunction occurring after cardiac surgery. The pathogenesis of POCD after cardiac surgery includes cerebral microembolism, neuroinflammation, and cryptogenic strokes. Risk factors are associated with advanced age, diminished preoperative cognitive status, and anesthesia. Cognitive function screening tools used for pre- and postoperative assessments can detect changes in patients' cognitive levels in a timely manner. The timely provision of appropriate rehabilitation methods, including cognitive function training, exercise training, transcranial direct current stimulation, and perioperative acupuncture, is crucial, with emerging technologies such as virtual reality playing an increasingly significant role. In conclusion, POCD is a common postoperative complication in elderly cardiac surgery patients, with age and reduced preoperative cognitive function being the primary risk factors. A comprehensive rehabilitation strategy can more effectively address postoperative cognitive dysfunction in patients.

摘要

术后认知功能障碍(POCD)是老年患者心脏手术后常见的中枢神经系统并发症。本综述旨在概述心脏手术后发生的认知功能障碍的病因、危险因素、诊断评估和康复策略。心脏手术后POCD的发病机制包括脑微栓塞、神经炎症和隐源性卒中。危险因素与高龄、术前认知状态减退和麻醉有关。用于术前和术后评估的认知功能筛查工具可以及时检测患者认知水平的变化。及时提供适当的康复方法,包括认知功能训练、运动训练、经颅直流电刺激和围手术期针灸,至关重要,虚拟现实等新兴技术发挥着越来越重要的作用。总之,POCD是老年心脏手术患者常见的术后并发症,年龄和术前认知功能减退是主要危险因素。综合康复策略可以更有效地解决患者术后认知功能障碍问题。