通过多层计算机断层扫描探索红细胞分布宽度在主动脉瓣钙化评估中的预后作用。
Exploring the Prognostic Role of Red Blood Cell Distribution Width in Aortic Valve Calcification Evaluations via Multi-Slice Computed Tomography.
作者信息
Zeng Yiyao, Jin Fulu, Wang Li, Wang Peiyu, Xiong Hui, Zhou Yafeng, Jiang Yufeng, Zhao Liangping
机构信息
Department of Cardiology, The Fourth Hospital Affiliated to Soochow University, Medical Center of Soochow University, Suzhou Dushu Lake Hospital, 215000 Suzhou, Jiangsu, China.
Department of Cardiology, The Second Affiliated Hospital of Soochow University, 215000 Suzhou, Jiangsu, China.
出版信息
Rev Cardiovasc Med. 2024 Dec 12;25(12):437. doi: 10.31083/j.rcm2512437. eCollection 2024 Dec.
BACKGROUND
Previous reports have indicated an association between red blood cell distribution width (RDW) and cardiovascular disease. However, few relevant studies exist on the relationship between RDW and aortic valve calcification (AVC). Explore the correlation and predictive value of RDW concerning the occurrence and severity of aortic valve calcification.
METHODS
Blood examination results were analyzed from 1720 hospitalized patients at the Second Affiliated Hospital of Soochow University. Logistic regression analysis and the Cox proportional hazards model examined the relationship between RDW and the incidence and severity of AVC.
RESULTS
The RDW value in cases with AVC was significantly higher than in the control group. Red cell distribution width-standard deviation (RDW-SD) and red cell distribution width-coefficient of variation (RDW-CV) increased with calcification severity. Both RDW-SD and RDW-CV demonstrated high predictive values for the occurrence of aortic valve calcification.
CONCLUSIONS
Red blood cell distribution width significantly correlated with the occurrence and severity of aortic valve calcification.
背景
既往报告表明红细胞分布宽度（RDW）与心血管疾病之间存在关联。然而，关于RDW与主动脉瓣钙化（AVC）之间关系的相关研究较少。探讨RDW与主动脉瓣钙化发生及严重程度的相关性和预测价值。
方法
分析苏州大学附属第二医院1720例住院患者的血液检查结果。采用逻辑回归分析和Cox比例风险模型检验RDW与AVC发生率及严重程度之间的关系。
结果
AVC患者的RDW值显著高于对照组。红细胞分布宽度标准差（RDW-SD）和红细胞分布宽度变异系数（RDW-CV）随钙化严重程度增加而升高。RDW-SD和RDW-CV对主动脉瓣钙化的发生均具有较高的预测价值。
结论
红细胞分布宽度与主动脉瓣钙化的发生及严重程度显著相关。
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