Wolffsohn James S, Semp David A, Dutta Debarun, Jones Lyndon, Craig Jennifer P
Optometry and Vision Science Research Group, College of Health and Life Sciences, Aston University, Birmingham, United Kingdom; Department of Ophthalmology, Aotearoa New Zealand National Eye Centre, The University of Auckland, New Zealand; Centre for Ocular Research and Education (CORE), School of Optometry and Vision Science, University of Waterloo, Canada.
Optometry and Vision Science Research Group, College of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Ocul Surf. 2025 Apr;36:164-172. doi: 10.1016/j.jtos.2024.12.008. Epub 2024 Dec 30.
To understand current clinical management of dry eye disease (DED), based on its perceived severity and subtype, by practitioners across the world.
The content of the anonymous survey was chosen to reflect the DED management strategies reported by the Tear Film and Ocular Surface Society (TFOS) second Dry Eye Workshop (DEWS II). Questions were designed to ascertain practitioner treatment choice, depending on the subtype and severity of DED. It was first created in English and then translated/back-translated into 14 languages for online completion.
Completed surveys were received from 905 eye care practitioners (52 % optometrists and 42 % ophthalmologists) from across the globe. Many treatment strategies for DED were observed to be utilised by respondents, independent of severity and subtype, the most common being advice (82 %), low (82 %) and high (81 %) viscosity unpreserved lubricants and lid wipes/scrubs (79 %). Several treatments were prescribed across all severity levels (scaled from 1 mild to 10 severe), such as advice (median 4.5, range 4.8), artificial tears (median 5.1, range 4.6) and nutritional supplements (median 5.3, range 4.2). Others were prescribed more frequently with increasing disease severity, for instance, biologics (median 8.2, range 2.8) and surgical approaches (median 8.1, range 2.2). While a similar number of practitioners reported prescribing advice, artificial tears and anti-inflammatories regardless of DED subtype, the commonly reported approaches for aqueous deficient DED were punctal occlusion, therapeutic contact lenses and secretagogues, while the use of oral essential fatty acids, topical lipid-containing products, lid hygiene and lid warming were the preferred management choices for evaporative DED.
There remains great variability in clinical approaches to DED management and until research-evidence definitively informs improved guidance, data from this survey may be useful for clinicians to benchmark their practice.
了解全球从业者基于干眼疾病(DED)的感知严重程度和亚型的当前临床管理情况。
匿名调查的内容旨在反映泪膜与眼表协会(TFOS)第二届干眼研讨会(DEWS II)报告的干眼管理策略。问题旨在确定从业者根据干眼的亚型和严重程度所做出的治疗选择。该调查最初以英文创建,然后翻译成14种语言并进行回译以供在线填写。
收到了来自全球905名眼保健从业者(52%为验光师,42%为眼科医生)的完整调查问卷。观察到许多干眼治疗策略被受访者采用,与严重程度和亚型无关,最常见的是建议(82%)、低(82%)和高(81%)粘度的无防腐剂润滑剂以及眼睑擦拭/擦洗(79%)。在所有严重程度级别(从1级轻度到10级重度)都有几种治疗方法被开具,如建议(中位数4.5,范围4.8)、人工泪液(中位数5.1,范围4.6)和营养补充剂(中位数5.3,范围4.2)。其他一些治疗方法随着疾病严重程度的增加而开具得更频繁,例如生物制剂(中位数8.2,范围2.8)和手术方法(中位数8.1,范围2.2)。虽然有相似数量的从业者报告无论干眼亚型如何都开具建议、人工泪液和抗炎药,但对于水液缺乏型干眼,常见的报告方法是泪点栓塞、治疗性隐形眼镜和促分泌剂,而口服必需脂肪酸、局部含脂质产品、眼睑卫生和眼睑热敷是蒸发型干眼的首选管理方法。
干眼管理的临床方法仍然存在很大差异,在研究证据明确提供改进指导之前,本次调查的数据可能有助于临床医生衡量自己的实践。