Direct effect of lipid emulsion treatment on local anesthetic systemic toxicity.
作者信息
Sohn Ju-Tae
机构信息
Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.
Institute of Medical Science, Gyeongsang National University, Jinju, Korea.
出版信息
Clin Exp Emerg Med. 2024 Dec;11(4):399-401. doi: 10.15441/ceem.24.326. Epub 2024 Dec 24.
Abstract
摘要
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本文引用的文献
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Local anesthetic systemic toxicity: awareness, recognition, and risk mitigation in the emergency department.局部麻醉药全身毒性：急诊科的认识、识别及风险缓解
Clin Exp Emerg Med. 2024 Jun;11(2):121-126. doi: 10.15441/ceem.24.231. Epub 2024 May 23.
2
Mechanisms underlying lipid emulsion resuscitation for drug toxicity: a narrative review.脂质乳剂复苏在药物毒性中的作用机制：叙述性综述。
Korean J Anesthesiol. 2023 Jun;76(3):171-182. doi: 10.4097/kja.23031. Epub 2023 Jan 26.
3
Anesthetic management of patients with carnitine deficiency or a defect of the fatty acid β-oxidation pathway: A narrative review.肉碱缺乏或脂肪酸β-氧化途径缺陷患者的麻醉管理：叙述性综述。
Medicine (Baltimore). 2022 Feb 18;101(7):e28853. doi: 10.1097/MD.0000000000028853.
4
Lipid emulsions attenuate the inhibition of carnitine acylcarnitine translocase induced by toxic doses of local anesthetics in rat cardiomyoblasts.脂质乳剂可减轻毒性局部麻醉药在大鼠心肌细胞中诱导的肉毒碱酰基辅酶 A 转移酶抑制作用。
Hum Exp Toxicol. 2022 Jan-Dec;41:9603271211065978. doi: 10.1177/09603271211065978.
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Bupivacaine-induced contraction is attenuated by endothelial nitric oxide release modulated by activation of both stimulatory and inhibitory phosphorylation (Ser1177 and Thr495) of endothelial nitric oxide synthase.布比卡因诱导的收缩通过内皮型一氧化氮合酶的刺激和抑制磷酸化（Ser1177 和 Thr495）调节的内皮型一氧化氮释放而减弱。
Eur J Pharmacol. 2019 Jun 15;853:121-128. doi: 10.1016/j.ejphar.2019.03.026. Epub 2019 Mar 15.
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Ropivacaine-induced contraction is attenuated by both endothelial nitric oxide and voltage-dependent potassium channels in isolated rat aortae.罗哌卡因诱导的收缩在分离的大鼠主动脉中被内皮一氧化氮和电压依赖性钾通道所抑制。
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