Bhat Sajad A, Guroo Farooq A, Koul Ajaz N, Mantoo Suhail, Siraj Farhana, Soharwardy Mohammad Yonus
Internal Medicine, Division of Infectious Diseases, Sher-I-Kashmir Institute Of Medical Sciences, Srinagar, IND.
Internal Medicine, Division of Infectious Diseases, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, IND.
Cureus. 2024 Dec 2;16(12):e74969. doi: 10.7759/cureus.74969. eCollection 2024 Dec.
Brucellosis is one of the most common zoonotic infections present worldwide. It usually presents as a febrile illness but can affect multiple organs of the body. Although cardiac involvement in brucellosis is rare, it is a fatal organ involvement. The endocarditis is the most common cause of death among patients with Brucella infection. The management of complications of infective endocarditis like stroke requires a multispecialty approach. The Brucella being a fastidious organism requires proper culture technique for growth. The serological methods of diagnosis have limited value in areas with high seroprevalence of brucellosis. We present a case series of three patients who had Brucella endocarditis with varied complications and courses of illness. The practice of a prolonged culture of blood for seven days ensured growth on the culture medium. All three patients were managed with medical therapy only, with a favorable outcome in two patients. In this case series, we have highlighted the importance of proper diagnostic methods and early surgical intervention when indicated.
布鲁氏菌病是全球最常见的人畜共患感染病之一。它通常表现为发热性疾病，但可累及身体多个器官。虽然布鲁氏菌病累及心脏罕见，但却是一种致命的器官受累情况。感染性心内膜炎是布鲁氏菌感染患者最常见的死亡原因。对于感染性心内膜炎并发症如中风的治疗需要多学科方法。布鲁氏菌是一种苛求菌，需要适当的培养技术才能生长。在布鲁氏菌病血清阳性率高的地区，血清学诊断方法价值有限。我们报告了一组三例布鲁氏菌性心内膜炎患者的病例系列，其并发症和病程各异。延长血液培养7天的做法确保了在培养基上生长。所有三名患者仅接受药物治疗，两名患者预后良好。在这个病例系列中，我们强调了正确诊断方法和在有指征时早期手术干预的重要性。
