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经导管主动脉瓣置换术前突出冠状动脉支架的扩张以最小化相互作用——一项可行性研究

Flaring of Protruding Coronary Stents Before Transcatheter Aortic Valve Replacement to Minimize Interaction-A Feasibility Study.

作者信息

Fang Jonathan X, Engel Gonzalez Pedro, Villablanca Pedro A, Frisoli Tiberio M, Kamel-Abusalha Louie B, Lee James C, Giustino Gennaro, Wang Dee Dee, O'Neill William W, O'Neill Brian P

机构信息

Center for Structural Heart Disease, Henry Ford Health System, Detroit, Michigan, USA.

College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, USA.

出版信息

Catheter Cardiovasc Interv. 2025 Mar;105(4):772-782. doi: 10.1002/ccd.31378. Epub 2025 Jan 2.

Abstract

BACKGROUND

Protruding coronary artery stents can adversely affect transcatheter aortic valve replacement (TAVR) procedure. Current evidence on the topic is limited.

AIMS

We aim to study the clinical feasibility and safety of flaring of protruding coronary artery stents before TAVR to reduce interaction with transcatheter heart valves.

METHODS

Twenty consecutive patients with 22 protruding coronary stents were optimized with a dual-diameter balloon before TAVR. Procedural success, stent and valve geometry on angiogram, periprocedural and subsequent clinical outcomes as well as valve hemodynamics on echocardiography were evaluated.

RESULTS

Procedural success was achieved in 100% of coronary procedure and TAVR without any major complication directly related to the flaring of stents. There was no coronary artery obstruction after TAVR or visible stent or valve deformity. All valves had normal hemodynamics immediately post-deployment with none having clinically significant aortic insufficiency. One patient had inpatient mortality unrelated to coronary stent optimization. One valve had hemodynamic valve degeneration on follow-up which was unrelated to coronary stent flaring and the patient was asymptomatic.

CONCLUSION

Flaring of protruding coronary stents before TAVR is technically feasible and safe and can potentially minimize stent-valve interaction for during of after TAVR.

摘要

背景

突出的冠状动脉支架会对经导管主动脉瓣置换术(TAVR)产生不利影响。目前关于该主题的证据有限。

目的

我们旨在研究在TAVR之前对突出的冠状动脉支架进行扩张的临床可行性和安全性,以减少与经导管心脏瓣膜的相互作用。

方法

连续20例患有22个突出冠状动脉支架的患者在TAVR之前用双直径球囊进行优化。评估手术成功率、血管造影上的支架和瓣膜几何形状、围手术期及后续临床结果以及超声心动图上的瓣膜血流动力学。

结果

100%的冠状动脉手术和TAVR取得了手术成功,没有任何与支架扩张直接相关的重大并发症。TAVR后没有冠状动脉阻塞,也没有可见的支架或瓣膜变形。所有瓣膜在植入后立即具有正常的血流动力学,没有临床上显著的主动脉瓣关闭不全。1例患者住院死亡与冠状动脉支架优化无关。1个瓣膜在随访中出现血流动力学瓣膜退变,与冠状动脉支架扩张无关,且该患者无症状。

结论

在TAVR之前对突出的冠状动脉支架进行扩张在技术上是可行和安全的,并且有可能在TAVR期间或之后将支架与瓣膜的相互作用降至最低。

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