Wu A, Zwicker R D, Sternick E S
Med Phys. 1985 Jan-Feb;12(1):27-31. doi: 10.1118/1.595733.
A new calculation procedure for interstitial implants with I-125 seeds is presented. The total activity of I-125 seeds required to deliver a net minimum dose of 1 Gy is also given as a function of implant volume for various seed spacings. This will permit clinicians to prescribe a specific dose for patients as a primary or boost treatment. Elongation and shape corrections are studied. Discussions and comparisons with other dosimetric calculations such as "matched" peripheral dose, average minimum dose, and minimum peripheral dose are made. The results indicate that for a fixed total activity the net minimum dose is relatively insensitive to variations in seed spacing and individual seed activity.
本文提出了一种用于碘-125籽源组织间植入的新计算程序。还给出了在不同籽源间距下，为达到1 Gy的净最小剂量所需的碘-125籽源的总活度与植入体积的函数关系。这将使临床医生能够为患者开出作为主要治疗或增强治疗的特定剂量。研究了伸长和形状校正。并与其他剂量计算方法进行了讨论和比较，如“匹配”周边剂量、平均最小剂量和最小周边剂量。结果表明，对于固定的总活度，净最小剂量对籽源间距和单个籽源活度的变化相对不敏感。
