Layer Yannik Christian, Faby Sebastian, Haase Viktor, Schmidt Bernhard, Mesropyan Narine, Kupczyk Patrick A, Isaak Alexander, Dell Tatjana, Luetkens Julian A, Kuetting Daniel
From the Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany (Y.C.L., N.M., P.A.K., A.I., T.D., J.A.L., D.K.); and Siemens Healthineers AG, Erlangen, Germany (S.F., V.H., B.S.).
Invest Radiol. 2025 Jan 3. doi: 10.1097/RLI.0000000000001149.
The aim of this study was to assess the impact of an iterative metal artifact reduction (iMAR) algorithm combined with virtual monoenergetic images (VMIs) for artifact reduction in photon-counting detector computed tomography (PCDCT) during interventions.
Using an abdominal phantom, we conducted evaluations on the efficacy of iMAR and VMIs for mitigating image artifacts during interventions on a PCDCT. Four different puncture devices were employed under 2 scan modes (QuantumSn at 100 kV, Quantumplus at 140 kV) to simulate various clinical scenarios. Image reconstructions were initially performed without iMAR and subsequently with iMAR settings. The latter was tested with 7 different metal presets for each case. Furthermore, iMAR-reconstructed images were paired with VMIs at energy levels of 70 keV, 110 keV, 150 keV, and 190 keV. Qualitative assessments were conducted to evaluate image quality, artifact expression, and the emergence of new artifacts using a Likert scale. Image quality was rated on a scale of 1 (nondiagnostic) to 5 (excellent), whereas artifact severity was rated from 0 (none) to 5 (massive). Preferences for specific iMAR presets were documented. Quantitative analysis involved calculating Hounsfield unit (HU) differences between artifact-rich and artifact-free tissues.
Overall, 96 different scanning series were evaluated. The optimal combination for artifact reduction was found to be iMAR neurocoils with VMIs at 150 keV and 190 keV, showcasing the most substantial reduction in artifacts with a median rating of 1 (standard: 4). VMIs at higher keV levels, such as 190 keV, resulted in reduced image quality, as indicated by a median rating of 3 (compared with 70 keV with a median of 5). Newly emerged artifact expression related to reconstructions varied among intervention devices, with iMAR thoracic coils exhibiting the least extent of artifacts (median: 2) and iMAR neurocoils displaying the most pronounced artifacts (median: 4). Qualitative analysis favored the combination of iMAR neurocoils with VMIs at 70 keV, showcasing the best results. Conversely, quantitative analysis revealed that the combination of iMAR neurocoils with VMIs at 190 keV yielded the best results, with an average artifact expression of 20.06 HU (standard: 167.98 HU; P < 0.0001).
The study underscores a substantial reduction in artifacts associated with intervention devices during PCDCT scans through the synergistic application of VMI and iMAR techniques. Specifically, the combination of VMIs at 70 keV with iMAR neurocoils was preferred, leading to enhanced diagnostic assessability of surrounding tissues and target lesions. The study demonstrates the potential of iMAR and VMIs for PCDCT-guided interventions. These advancements could improve accuracy, safety, efficiency, and patient outcomes in clinical practice.
本研究旨在评估迭代金属伪影减少(iMAR)算法与虚拟单能图像(VMI)相结合对光子计数探测器计算机断层扫描(PCDCT)介入过程中伪影减少的影响。
使用腹部体模,我们对iMAR和VMI在PCDCT介入过程中减轻图像伪影的效果进行了评估。在2种扫描模式(100 kV的QuantumSn、140 kV的Quantumplus)下使用4种不同的穿刺装置来模拟各种临床场景。图像重建最初在不使用iMAR的情况下进行,随后使用iMAR设置进行。每种情况使用7种不同的金属预设对后者进行测试。此外,iMAR重建图像与70 keV、110 keV、150 keV和190 keV能量水平的VMI进行配对。使用李克特量表进行定性评估,以评估图像质量、伪影表现和新伪影的出现情况。图像质量按1(无法诊断)至5(优秀)评分,而伪影严重程度按0(无)至5(大量)评分。记录对特定iMAR预设的偏好。定量分析涉及计算富含伪影组织和无伪影组织之间的亨氏单位(HU)差异。
总体而言,共评估了96个不同的扫描系列。发现减少伪影的最佳组合是iMAR神经线圈与150 keV和190 keV的VMI,伪影减少最为显著,中位数评分为1(标准:4)。较高keV水平(如190 keV)的VMI导致图像质量下降,中位数评分为3(与70 keV的中位数5相比)。与重建相关的新出现的伪影表现在介入装置之间有所不同,iMAR胸部线圈的伪影程度最小(中位数:2),iMAR神经线圈的伪影最为明显(中位数:4)。定性分析支持iMAR神经线圈与70 keV的VMI相结合,显示出最佳结果。相反,定量分析表明,iMAR神经线圈与190 keV的VMI相结合产生了最佳结果,平均伪影表现为20.06 HU(标准:167.98 HU;P < 0.0001)。
该研究强调了通过VMI和iMAR技术的协同应用,在PCDCT扫描期间与介入装置相关的伪影大幅减少。具体而言,可以优先选择70 keV的VMI与iMAR神经线圈相结合,从而提高对周围组织和目标病变的诊断可评估性。该研究证明了iMAR和VMI在PCDCT引导介入中的潜力。这些进展可以提高临床实践中的准确性、安全性、效率和患者预后。