Faggioni Michela, Giri Jay, Glassmoyer Lauren, Kobayashi Taisei
Division of Cardiovascular Medicine, Department of Medicine, University of California, San Francisco, California, USA.
Cardiovascular Outcomes, Quality, and Evaluative Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Annu Rev Med. 2025 Jan;76(1):327-337. doi: 10.1146/annurev-med-050423-085457. Epub 2025 Jan 16.
Over the past decade, new modalities have emerged to treat acute pulmonary embolism (PE). However, PE remains a leading cause of morbidity and mortality worldwide. In the absence of robust clinical trial data and definitive guidelines and recommendations for a variety of clinical situations, individual patient treatment decisions have become paradoxically more challenging as innovation in the space has grown. In this review, we discuss a practical and current approach to patients diagnosed with PE, focusing on their risk stratification and treatment selection.
在过去十年中，出现了治疗急性肺栓塞（PE）的新方法。然而，肺栓塞仍是全球发病和死亡的主要原因。由于缺乏针对各种临床情况的有力临床试验数据以及明确的指南和建议，随着该领域创新的增加，个体患者的治疗决策反而变得更具挑战性。在本综述中，我们讨论了一种针对诊断为肺栓塞患者的实用且最新的方法，重点关注他们的风险分层和治疗选择。
