• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Evidence of DNA repair in organ cultures of hamster tracheal epithelium following exposure to gas phase singlet oxygen.

作者信息

Schiff L J, Eisenberg W C, Taylor K

出版信息

Mutat Res. 1985 Jan-Feb;142(1-2):41-4. doi: 10.1016/s0165-7992(85)80010-5.

DOI:10.1016/s0165-7992(85)80010-5
PMID:3974597
Abstract

Autoradiographic identification of unscheduled DNA synthesis (UDS) in short-term organ culture of hamster tracheal epithelium has been used as a predictive test for mutagenic and/or carcinogenic compounds. Tracheal explants were treated for 2 h with singlet delta oxygen plus [3H]thymidine. Silver grains over the nuclei of epithelial cells from the superficial layer of the mucosa were observed, indicating UDS. Control cultures, exposed to the gas phase without singlet oxygen, failed to elicit UDS.

摘要

相似文献

1
Evidence of DNA repair in organ cultures of hamster tracheal epithelium following exposure to gas phase singlet oxygen.
Mutat Res. 1985 Jan-Feb;142(1-2):41-4. doi: 10.1016/s0165-7992(85)80010-5.
2
Biological effects of singlet delta oxygen on respiratory tract epithelium.
Experientia. 1984 May 15;40(5):514-5. doi: 10.1007/BF01952414.
3
Vitamin A and beta-carotene influence the level of benzo[a]pyrene-induced DNA adducts and DNA-repair activities in hamster tracheal epithelium in organ culture.维生素A和β-胡萝卜素影响器官培养的仓鼠气管上皮中苯并[a]芘诱导的DNA加合物水平和DNA修复活性。
Cancer Lett. 1995 May 8;91(2):205-14. doi: 10.1016/0304-3835(95)03740-n.
4
Cytotoxic effects of singlet oxygen.单线态氧的细胞毒性作用。
Environ Health Perspect. 1987 Dec;76:199-203. doi: 10.1289/ehp.8776199.
5
Autoradiographic demonstration of DNA repair synthesis in rat tracheal epithelium treated with chemical carcinogen in vitro.体外化学致癌物处理的大鼠气管上皮细胞DNA修复合成的放射自显影证明
Cancer Res. 1980 Aug;40(8 Pt 1):2898-902.
6
Formation and repair of benzo[a]pyrene-DNA adducts in cultured hamster tracheal epithelium determined by 32P-postlabeling analysis and unscheduled DNA synthesis.通过³²P后标记分析和非预定DNA合成测定培养的仓鼠气管上皮中苯并[a]芘-DNA加合物的形成与修复
Carcinogenesis. 1993 Mar;14(3):463-7. doi: 10.1093/carcin/14.3.463.
7
Unscheduled DNA synthesis in rat tracheal epithelial cells, hepatocytes and spermatocytes following exposure to methyl chloride in vitro and in vivo.大鼠气管上皮细胞、肝细胞和精母细胞在体内外暴露于氯甲烷后出现的非程序性DNA合成。
Mutat Res. 1986 Sep;162(2):219-24. doi: 10.1016/0027-5107(86)90088-6.
8
DNA adduct formation and repair in hamster and rat tracheas exposed to benzo[a]pyrene in organ culture.在器官培养中暴露于苯并[a]芘的仓鼠和大鼠气管中的DNA加合物形成与修复
Carcinogenesis. 1994 Apr;15(4):661-5. doi: 10.1093/carcin/15.4.661.
9
Detection of chemical carcinogens by assay of unscheduled DNA synthesis in rat tracheal epithelium in short-term organ culture.通过短期器官培养中大鼠气管上皮细胞非程序性DNA合成检测化学致癌物。
J Cancer Res Clin Oncol. 1981;102(2):115-26. doi: 10.1007/BF00410663.
10
Unscheduled DNA synthesis in human bronchial epithelium treated with various chemical carcinogens in vitro.体外经多种化学致癌物处理的人支气管上皮细胞中的非程序性DNA合成。
J Natl Cancer Inst. 1984 Jul;73(1):101-6.

引用本文的文献

1
Cytotoxic effects of singlet oxygen.单线态氧的细胞毒性作用。
Environ Health Perspect. 1987 Dec;76:199-203. doi: 10.1289/ehp.8776199.