Bragin A G, Vinogradova O S, Mironov S F
Neirofiziologiia. 1985;17(1):61-9.
Neuronal activity of the septal and hippocampal grafts, developing in the anterior eye chamber of the rat for 3-6 months was recorded extracellularly in curarized or cerveau isolé animals. While the units of isolated septum had background activity of regular, irregular and rhythmic burst type, the hippocampal units displayed no background discharges or produced very low-frequency population spikes. In the paired septal-hippocampal grafts neurons of the hippocampus possessed the same types of activity, as that of the septum. Spontaneous epileptiform phenomena were observed in many paired grafts; such phenomena were easily provoked by mild electrical stimulation of one of the grafts. Superfusion with low Ca2+, high Mg2+ medium abolished spontaneous activity in most of hippocampal units but not in septal units. Epileptic discharges were also partly suppressed.
在箭毒化或孤立脑动物中，对在大鼠前房内发育3 - 6个月的隔区和海马移植组织的神经元活动进行了细胞外记录。孤立隔区的神经元具有规则、不规则和节律性爆发型的背景活动，而海马神经元则没有背景放电或产生非常低频的群体峰电位。在配对的隔区 - 海马移植组织中，海马神经元具有与隔区相同类型的活动。在许多配对移植组织中观察到自发性癫痫样现象；这种现象很容易通过对其中一个移植组织进行轻度电刺激而诱发。用低钙、高镁培养基灌注可消除大多数海马神经元的自发活动，但隔区神经元不受影响。癫痫放电也部分受到抑制。
