Wirtz Andrea L, Reisner Sari L, Cole S Wilson, Adams Darya, Davids J D, Cohen Alison K, Brown Carter, Miller Marissa, Poteat Tonia C
Department of Epidemiology, Center for Public Health and Human Rights, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Sci Rep. 2025 Jan 2;15(1):383. doi: 10.1038/s41598-024-84519-5.
Despite recommendations in the US National Research Action Plan on Long COVID, gender identity is rarely reported in research and surveillance used to guide public health programming and clinical care. We analyzed data from a cross-sectional study of COVID-19 in a nationwide sample of transgender and nonbinary (TNB) people (N = 2,134). Participants were surveyed between June 14, 2021 and May 1, 2022. Data were restricted to 817 participants who reported confirmed or suspected COVID-19 to estimate the prevalence of long COVID, defined as symptoms persisting for ≥ 3 months. Ten percent of participants with a history of COVID-19 reported symptom duration consistent with long COVID, ranging from 4.8% to 12.9% across gender identities. Long COVID was most common in transmasculine and nonbinary people assigned female sex at birth. There was no evidence of an association with reported hormone therapy, supporting current recommendations that prioritize gender-affirming care during treatment for long COVID. As a condition which profoundly impacts health and productivity, long COVID is likely to exacerbate existing disparities. Principles of equity demand that we reduce barriers to prevention, diagnosis, and care for long COVID, and ensure that research and surveillance are inclusive of TNB people and disaggregate findings by gender identity.
尽管美国国家新冠后状况研究行动计划中有相关建议，但在用于指导公共卫生规划和临床护理的研究及监测中，很少报告性别认同情况。我们分析了一项针对全国范围内跨性别者和非二元性别者（TNB）（N = 2134）的新冠病毒横断面研究数据。参与者于2021年6月14日至2022年5月1日期间接受调查。数据仅限于817名报告确诊或疑似感染新冠病毒的参与者，以估计新冠后状况的患病率，新冠后状况定义为症状持续≥3个月。有新冠病毒感染史的参与者中，10%报告症状持续时间符合新冠后状况，不同性别认同者的比例在4.8%至12.9%之间。新冠后状况在出生时被认定为女性的跨男性和非二元性别者中最为常见。没有证据表明与所报告的激素治疗有关联，这支持了当前在新冠后状况治疗期间优先提供性别肯定护理的建议。作为一种对健康和生产力有深远影响的状况，新冠后状况可能会加剧现有的差异。公平原则要求我们减少新冠后状况预防、诊断和护理的障碍，并确保研究和监测纳入跨性别者和非二元性别者，并按性别认同对结果进行分类。
