Shah Richa, Hanna Nader Mounir, Loo Ching Ee, David Michael, Mafra Allini, Fink Hanna, McFerran Ethna, Garcia Montse, Ghodssighassemabadi Robabeh, Acharya Suryakanta, Niyibaga Jean, Langselius Oliver, Frick Clara, Lasebikan Nwamaka, Vignat Jerome, Steinberg Julia, Hughes Suzanne, Kircher Colleen Elizabeth, Goldie Catherine Lindsay, Egger Sam, Sullivan Richard, Ginsburg Ophira, Bray Freddie, Caruana Michael, Hui Harriet, Ilbawi André Michel, Canfell Karen, Soerjomataram Isabelle
Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Department of Surgery, Queen's University, Kingston, Ontario, Canada.
Nat Cancer. 2025 Jan;6(1):194-204. doi: 10.1038/s43018-024-00880-4. Epub 2025 Jan 2.
The coronavirus disease 2019 pandemic substantially impacted the delivery of cancer services and programs. Here we reviewed and synthesized the global scale and impact of pandemic-related delays and disruptions on cancer services, including diagnosis, diagnostic procedures, screening, treatment and supportive and palliative care. Based on data from 245 articles in 46 countries, we observed declines in the number of cancer screening participation (39.0%), diagnoses (23.0%), diagnostic procedures (24.0%) and treatment (28.0%), ranging from a 15.0% decline for radiotherapy to a 35.0% decline for systemic treatment during the pandemic compared to during the prepandemic period. Medium-human development index (HDI) category countries experienced greater reductions than high- and very-high-HDI countries. Missing data from low-HDI countries emphasize the need for increased investments in cancer surveillance and research in these settings. PROSPERO registration: CRD42022301816.
2019年冠状病毒病大流行对癌症服务和项目的提供产生了重大影响。在此，我们回顾并综合了全球范围内大流行相关的延误和干扰对癌症服务的规模及影响，包括诊断、诊断程序、筛查、治疗以及支持性和姑息性护理。基于46个国家245篇文章的数据，我们观察到癌症筛查参与人数（下降39.0%）、诊断（下降23.0%）、诊断程序（下降24.0%）和治疗（下降28.0%）均有所减少，与大流行前时期相比，大流行期间放疗下降15.0%，全身治疗下降35.0%。中等人类发展指数（HDI）类别的国家比高HDI和极高HDI国家经历了更大幅度的减少。低HDI国家的缺失数据凸显了在这些地区增加癌症监测和研究投资的必要性。国际系统评价前瞻性注册库（PROSPERO）注册号：CRD42022301816。
