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本文引用的文献

1
The Bergen 4-day treatment for social anxiety disorder: a pilot study.卑尔根 4 天治疗社交焦虑障碍:一项试点研究。
BMC Psychiatry. 2024 Feb 21;24(1):145. doi: 10.1186/s12888-024-05607-4.
2
The Bergen 4-day treatment for panic disorder: adapting to COVID-19 restrictions with a hybrid approach of face-to-face and videoconference modalities.贝根 4 天治疗惊恐障碍:采用面对面和视频会议相结合的混合模式适应 COVID-19 限制。
BMC Psychiatry. 2023 Aug 8;23(1):570. doi: 10.1186/s12888-023-05062-7.
3
The Bergen 4-day treatment for panic disorder: implementation in a rural clinical setting.卑尔根 4 天治疗惊恐障碍:在农村临床环境中的实施。
BMC Psychiatry. 2023 May 1;23(1):305. doi: 10.1186/s12888-023-04812-x.
4
Effective-and Tolerable: Acceptance and Side Effects of Intensified Exposure for Anxiety Disorders.有效且耐受:焦虑障碍强化暴露的接受度和副作用。
Behav Ther. 2023 May;54(3):427-443. doi: 10.1016/j.beth.2022.11.001. Epub 2022 Nov 9.
5
The Bergen 4-day treatment for panic disorder: replication and implementation in a new clinic.《惊恐障碍的卑尔根 4 天治疗方案:在新诊所的复制和实施》。
BMC Psychiatry. 2022 Nov 23;22(1):728. doi: 10.1186/s12888-022-04380-6.
6
Comparative efficacy and acceptability of psychotherapies for panic disorder with or without agoraphobia: systematic review and network meta-analysis of randomised controlled trials.伴有或不伴有广场恐惧症的惊恐障碍的心理治疗的疗效和可接受性比较:随机对照试验的系统评价和网络荟萃分析。
Br J Psychiatry. 2022 Sep;221(3):507-519. doi: 10.1192/bjp.2021.148.
7
Drug treatment for panic disorder with or without agoraphobia: systematic review and network meta-analysis of randomised controlled trials.伴有或不伴有广场恐惧症的惊恐障碍的药物治疗:随机对照试验的系统评价和网络荟萃分析。
BMJ. 2022 Jan 19;376:e066084. doi: 10.1136/bmj-2021-066084.
8
Implementation of the Bergen 4-Day Treatment for Obsessive Compulsive Disorder in Iceland.冰岛对强迫症实施卑尔根4日疗法。
Clin Neuropsychiatry. 2019 Feb;16(1):33-38.
9
Efficacy of temporally intensified exposure for anxiety disorders: A multicenter randomized clinical trial.时间强化暴露治疗焦虑障碍的疗效:一项多中心随机临床试验。
Depress Anxiety. 2021 Nov;38(11):1169-1181. doi: 10.1002/da.23204. Epub 2021 Jul 22.
10
Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder: A Randomized Clinical Trial.D-环丝氨酸对集中暴露和反应预防治疗难治性强迫症效果的影响:一项随机临床试验。
JAMA Netw Open. 2020 Aug 3;3(8):e2013249. doi: 10.1001/jamanetworkopen.2020.13249.

卑尔根针对农村临床环境中惊恐障碍患者的4天治疗:一项长期随访研究。

The Bergen 4-Day Treatment for panic disorder patients in a rural clinical setting: a long-term follow-up study.

作者信息

Eide Thorstein Olsen, Olsen Thorbjørn, Hansen Hans, Hansen Bjarne, Solem Stian, Hagen Kristen

机构信息

Department of Psychiatry, Molde Hospital, Møre og Romsdal Hospital Trust, Molde, Norway.

Center for Crisis Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.

出版信息

BMC Psychiatry. 2025 Jan 2;25(1):3. doi: 10.1186/s12888-024-06445-0.

DOI:10.1186/s12888-024-06445-0
PMID:39748386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11697728/
Abstract

BACKGROUND

The Bergen 4-Day Treatment (B4DT) is a concentrated cognitive behaviour therapy (CBT) approach that has shown promise in treating panic disorder (PD). However, the effectiveness of the B4DT, particularly regarding long-term outcomes in rural clinical settings, remains underexplored.

METHODS

A total of 58 patients were included using a naturalistic open-label trial design. Patients were assessed at 12-month follow-up. Measures included the Panic Disorder Severity Scale (PDSS), the Patient Health Questionnaire-9 (PHQ-9), and the Generalized Anxiety Disorder-7 scale (GAD-7).

RESULTS

The study revealed significant and lasting reductions in PD symptoms, with a high rate of remission maintained at 12-month follow-up (82.8%). Regarding the secondary outcomes, significant improvements in symptoms of depression and generalized anxiety were also shown.

CONCLUSIONS

The B4DT represents a promising treatment approach for PD, demonstrating stable long-term outcomes in rural settings. This finding supports the potential of concentrated CBT formats in achieving sustained symptom improvement in patients with PD, warranting further investigation and broader implementation.

TRIAL REGISTRATION

The study was reviewed by the Regional Committee for Medical Research Ethics Northern Norway, REK North (REK Nord2021/273145).

摘要

背景

卑尔根4日疗法(B4DT)是一种集中式认知行为疗法(CBT),在治疗惊恐障碍(PD)方面已显示出前景。然而,B4DT的有效性,特别是在农村临床环境中的长期疗效,仍未得到充分探索。

方法

采用自然主义开放标签试验设计,共纳入58例患者。在12个月的随访中对患者进行评估。测量指标包括惊恐障碍严重程度量表(PDSS)、患者健康问卷-9(PHQ-9)和广泛性焦虑障碍-7量表(GAD-7)。

结果

研究显示惊恐障碍症状有显著且持久的减轻,在12个月随访时维持了较高的缓解率(82.8%)。关于次要结果,抑郁和广泛性焦虑症状也有显著改善。

结论

B4DT是一种有前景的惊恐障碍治疗方法,在农村环境中显示出稳定的长期疗效。这一发现支持了集中式CBT形式在实现惊恐障碍患者症状持续改善方面的潜力,值得进一步研究和更广泛的应用。

试验注册

该研究经挪威北部地区医学研究伦理委员会(REK North,REK Nord2021/273145)审查。