卑尔根针对农村临床环境中惊恐障碍患者的4天治疗：一项长期随访研究。
The Bergen 4-Day Treatment for panic disorder patients in a rural clinical setting: a long-term follow-up study.
作者信息
Eide Thorstein Olsen, Olsen Thorbjørn, Hansen Hans, Hansen Bjarne, Solem Stian, Hagen Kristen
机构信息
Department of Psychiatry, Molde Hospital, Møre og Romsdal Hospital Trust, Molde, Norway.
Center for Crisis Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.
出版信息
BMC Psychiatry. 2025 Jan 2;25(1):3. doi: 10.1186/s12888-024-06445-0.
BACKGROUND
The Bergen 4-Day Treatment (B4DT) is a concentrated cognitive behaviour therapy (CBT) approach that has shown promise in treating panic disorder (PD). However, the effectiveness of the B4DT, particularly regarding long-term outcomes in rural clinical settings, remains underexplored.
METHODS
A total of 58 patients were included using a naturalistic open-label trial design. Patients were assessed at 12-month follow-up. Measures included the Panic Disorder Severity Scale (PDSS), the Patient Health Questionnaire-9 (PHQ-9), and the Generalized Anxiety Disorder-7 scale (GAD-7).
RESULTS
The study revealed significant and lasting reductions in PD symptoms, with a high rate of remission maintained at 12-month follow-up (82.8%). Regarding the secondary outcomes, significant improvements in symptoms of depression and generalized anxiety were also shown.
CONCLUSIONS
The B4DT represents a promising treatment approach for PD, demonstrating stable long-term outcomes in rural settings. This finding supports the potential of concentrated CBT formats in achieving sustained symptom improvement in patients with PD, warranting further investigation and broader implementation.
TRIAL REGISTRATION
The study was reviewed by the Regional Committee for Medical Research Ethics Northern Norway, REK North (REK Nord2021/273145).
背景
卑尔根4日疗法（B4DT）是一种集中式认知行为疗法（CBT），在治疗惊恐障碍（PD）方面已显示出前景。然而，B4DT的有效性，特别是在农村临床环境中的长期疗效，仍未得到充分探索。
方法
采用自然主义开放标签试验设计，共纳入58例患者。在12个月的随访中对患者进行评估。测量指标包括惊恐障碍严重程度量表（PDSS）、患者健康问卷-9（PHQ-9）和广泛性焦虑障碍-7量表（GAD-7）。
结果
研究显示惊恐障碍症状有显著且持久的减轻，在12个月随访时维持了较高的缓解率（82.8%）。关于次要结果，抑郁和广泛性焦虑症状也有显著改善。
结论
B4DT是一种有前景的惊恐障碍治疗方法，在农村环境中显示出稳定的长期疗效。这一发现支持了集中式CBT形式在实现惊恐障碍患者症状持续改善方面的潜力，值得进一步研究和更广泛的应用。
试验注册
该研究经挪威北部地区医学研究伦理委员会（REK North，REK Nord2021/273145）审查。
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