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维生素D缺乏与妊娠期糖尿病之间的关系:一项叙述性综述。

Relationship between vitamin D deficiency and gestational diabetes: a narrative review.

作者信息

Lin Caiqiong, Liu Haiwei

机构信息

Department of Endocrinology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.

出版信息

Front Endocrinol (Lausanne). 2024 Dec 19;15:1504930. doi: 10.3389/fendo.2024.1504930. eCollection 2024.

Abstract

Vitamin D, often referred to as the "sunshine vitamin," is an essential fat-soluble vitamin that plays a critical role in bone health and has been shown to improve insulin sensitivity and glucose tolerance. Vitamin D deficiency is prevalent among pregnant and pre-pregnancy women, which increases the risk of developing gestational diabetes mellitus (GDM), a common complication during pregnancy. Recent studies have explored various aspects of the relationship between vitamin D deficiency and GDM, including the mechanisms by which vitamin D affects glucose metabolism, the role of the vitamin D receptor gene, and the impact of routine vitamin D supplementation before and during pregnancy. This paper will review the current research progress in these areas.

摘要

维生素D常被称为“阳光维生素”,是一种必需的脂溶性维生素,对骨骼健康起着关键作用,并且已被证明可改善胰岛素敏感性和葡萄糖耐量。维生素D缺乏在孕妇和孕前女性中普遍存在,这增加了患妊娠期糖尿病(GDM)的风险,妊娠期糖尿病是孕期常见的并发症。最近的研究探讨了维生素D缺乏与GDM之间关系的各个方面,包括维生素D影响葡萄糖代谢的机制、维生素D受体基因的作用以及孕期前后常规补充维生素D的影响。本文将综述这些领域的当前研究进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3080/11693588/4ed65b9613e5/fendo-15-1504930-g001.jpg

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