Lin Caiqiong, Liu Haiwei
Department of Endocrinology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Front Endocrinol (Lausanne). 2024 Dec 19;15:1504930. doi: 10.3389/fendo.2024.1504930. eCollection 2024.
Vitamin D, often referred to as the "sunshine vitamin," is an essential fat-soluble vitamin that plays a critical role in bone health and has been shown to improve insulin sensitivity and glucose tolerance. Vitamin D deficiency is prevalent among pregnant and pre-pregnancy women, which increases the risk of developing gestational diabetes mellitus (GDM), a common complication during pregnancy. Recent studies have explored various aspects of the relationship between vitamin D deficiency and GDM, including the mechanisms by which vitamin D affects glucose metabolism, the role of the vitamin D receptor gene, and the impact of routine vitamin D supplementation before and during pregnancy. This paper will review the current research progress in these areas.
维生素D常被称为“阳光维生素”,是一种必需的脂溶性维生素,对骨骼健康起着关键作用,并且已被证明可改善胰岛素敏感性和葡萄糖耐量。维生素D缺乏在孕妇和孕前女性中普遍存在,这增加了患妊娠期糖尿病(GDM)的风险,妊娠期糖尿病是孕期常见的并发症。最近的研究探讨了维生素D缺乏与GDM之间关系的各个方面,包括维生素D影响葡萄糖代谢的机制、维生素D受体基因的作用以及孕期前后常规补充维生素D的影响。本文将综述这些领域的当前研究进展。